Concurrent reversible posterior leukoencephalopathy syndrome during peri-operative period of renal transplantation in one case

doi:10.3969/j.issn.2095-4344.2014.05.016

Abstract

Abstract:

BACKGROUND: Reversible posterior leukoencephalopathy syndrome is rarely reported, especially concurrent during perioperative period of renal transplantation. Due to its clinical manifestations similar to uremia, transplant doctors are easy to ignore or not timely diagnosis reversible posterior leukoencephalopathy syndrome, thus impacting its treatment.

OBJECTIVE: To discuss the clinical manifestations, imaging features, treatment experience and prognosis of patients with reversible posterior leukoencephalopathy syndrome concurrent during perioperative period of renal transplantation, in order to improve the diagnostic rate and therapeutic effect.

METHODS: We reviewed clinical data of one case of concurrent reversible posterior leukoencephalopathy syndrome during perioperative period of renal transplantation admitted at the General Hospital of Shenyang Military Region.

RESULTS AND CONCLUSION: From the 3^rdday postoperatively, the patient gradually experienced abnormal blood pressure, blurred vision, headache, seizures, disturbance of consciousness and mental and behavioral abnormalities. Early head CT showed low density in the left frontal lobe and corona radiate; and further MRI re-examination showed flake-shaped T1 and long T2 signals in the bilateral frontal lobe, hippocampus, parietal occipital cortex, and brainstem, as well as high signals on FLARI images at the corresponding parts. After active treatment, the clinical manifestations were improved. Retrospective analysis of clinical data of this case and review of relevant literature will provide clinical data for the diagnosis and treatment of concurrent reversible posterior leukoencephalopathy syndrome during perioperative period of renal transplantation.

中国组织工程研究杂志出版内容重点：肾移植；肝移植；移植；心脏移植；组织移植；皮肤移植；皮瓣移植；血管移植；器官移植；组织工程

全文链接：

Key words: kidney transplantation, posterior leukoencephalopathy syndrome, postoperative complications, magnetic resonance imaging, frontal lobe, hippocampus, cerebral cortex

CLC Number:

R318

Li Jian-zhong, Fan Lian-hui, Liu Long, Yang Hong-wei, Li Xin, Cao Zhi-qiang, He Long. Concurrent reversible posterior leukoencephalopathy syndrome during peri-operative period of renal transplantation in one case[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(5): 748-753.

Figures/Tables 1

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