Abstract:

BACKGROUND: Follow-up researches have shown that there is no statistically difference in safety between kidney donor and healthy person after kidney transplantation, even the donors will have better life quality. 

OBJECTIVE: To evaluate the safety of living-related kidney transplantation in living kidney donors.

METHODS: Ninety-four cases of kidney donors received 1-10 years follow-up through regular clinical follow-up, telephone follow-up and regular renal patients self-help groups to compare the changes of serum creatinine, hematuria, proteinuria and blood pressure and lipid level in the donors before and after kidney transplantation.

RESULTS AND CONCLUSION: The serum creatinine was significantly increased after nephrectomy (P < 0.01), but all the donors had normal serum creatinine levels and remained stable. There was no significant difference in serum creatinine level between the latest follow-up and discharge (P > 0.05). After nephrectomy, three cases (3.2%) suffered from hematuria, two cases (2.1%) had proteinuria, and improved after rest; six cases (6.4%) were subject to hypertension and six cases (6.4%) to hyperlipidemia. All of the donors were alive. The living donor nephrectomy is feasible and safe. Preoperative assessment and long-term postoperative follow-up can guarantee the safety of the donors.

Key words: kidney transplantation, living donors, proteinuria, hypertension