Chinese Journal of Tissue Engineering Research ›› 2018, Vol. 22 ›› Issue (18): 2831-2835.doi: 10.3969/j.issn.2095-4344.0873

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Compressive strength of the newly formed tibia after repair with human tooth bone graft

Fang Ming1, Wang Zhi-ying2, Cai Lu2   

  1. 1College of Education, Bohai University, Jinzhou 121004, Liaoning Province, China; 2Center of Dental Implant, the 2nd Affiliated Hospital of Jinzhou Medical University, Jinzhou 121001, Liaoning Province, China
  • Received:2018-05-16 Online:2018-06-28 Published:2018-06-28
  • Contact: Wang Zhi-ying, Professor, Center of Dental Implant, the 2nd Affiliated Hospital of Jinzhou Medical University, Jinzhou 121001, Liaoning Province, China
  • About author:Fang Ming, Master, Professor, College of Education, Bohai University, Jinzhou 121004, Liaoning Province, China
  • Supported by:

    the Liaoning Provincial Hospital Reform Project for Clinical Diagnosis and Treatment, No. LNCCL-C10-2015; the Scientific Research Project of Jinzhou Municipal Science and Technology Department, No. 15A1D33

Abstract:

BACKGROUND: Human tooth bone graft has been used for bone deficiency in dental implantation, but the strength and quality of newly formed bones with human tooth bone graft are in need of sound investigation.

OBJECTIVE: To investigate the compressive strength of newly formed rabbit tibia after repair with human tooth bone graft.

METHODS: Orthodontic teeth, loose molars, bicuspid premolars extracted from patients were taken to prepare human tooth bone grafts. Human tooth bone graft and bovine bone graft were independently placed into the rabbit tibia defects of 5 mm in diameter. Non-injured site served as control group.
RESULTS AND CONCLUSION: The newly formed rabbit tibia after repair with human tooth bone graft had more intact microstructure and higher maximum compressive strength and stiffness relative to that after repair with bovine bone graft. These findings indicate human tooth bone graft is superior to bovine bone graft in the repair of tibia defects in rabbits. 

Key words: Dental Implantation, Tibia, Tissue Engineering

CLC Number: