Biomechanical function of calcified cartilage zone based on finite element analysis

doi:10.3969/j.issn.2095-4344.0571

Abstract

Abstract:

BACKGROUND: Calcified cartilage zone is important for the stable connection between soft hyaline cartilage and hard subchondral bone. But the biomechanical role of calcified cartilage zone played in this process is poorly understood.

OBJECTIVE: To explore the biomechanical role of calcified cartilage zone using finite element analysis.

METHODS: Human normal femoral condyle specimen from a volunteer was obtained. According to the principle of bionics, a three-dimensional finite element model of osteochondral tissue was created with three compositions: hyaline cartilage, calcified cartilage zone and subchondral bone. The compression load (0.5-3.0 MPa) and shear load (0.1-0.5 MPa) were applied to the model respectively in order to analyze the stress distributions of three compositions.

RESULTS AND CONCLUSION: Under compression load and shear load, the maximum stress of hyaline cartilage was 0.15-0.86 MPa and 0.58-0.74 MPa, respectively. The maximum stress of calcified cartilage zone was 0.33-1.91 MPa and 1.27-1.62 MPa, respectively. The maximum stress of subchondral bone was 0.55-3.22 MPa and 2.36-2.98 MPa, respectively. Finite element analysis reveals the biomechanical role of calcified cartilage zone through the feature of its stress distribution. It mediates the load transfer from hyaline cartilage to subchondral bone in a stepwise-increase way, so that the load can transfer smoothly in three compositions of osteochondral tissue.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Cartilage, Bone and Bones, Finite Element Analysis, Biomechanics, Tissue Engineering

CLC Number:

R466

Chen Kaining, Ye Qing, Nong Mingshan, Luo Liuning, Yang Xing, Chen Cheng, Wang Fuyou. Biomechanical function of calcified cartilage zone based on finite element analysis[J]. Chinese Journal of Tissue Engineering Research, 2019, 23(4): 545-550.

Figures/Tables 3

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