Transforaminal lumbar interbody fusion for degenerative disc diseases: relationship between body mass index and revision rate

doi:10.3969/j.issn.2095-4344.0317

Abstract

Abstract:

BACKGROUND: With the increase of obesity population, more intension has been focused on its influence on spinal surgery, especially revision. However, effect of obesity on the revision after minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) remains unclear.

OBJECTIVE: To explore whether body mass index (BMI) of the patients with lumbar degenerative diseases will impact the revision rate following MIS-TLIF.

METHODS: Totally 143 patients undergoing single-segment MIS-TLIF were enrolled. The patients were allocated into four groups based on BMI: normal group (BMI < 25 kg/m²), overweight group (BMI of 25-29.9 kg/m²), obesity I group (BMI of 30-34.9 kg/m²), and obesity II-III group (BMI ≥ 35 kg/m²). The low back pain Visual Analogue Scale score at baseline, 6, 12 weeks, and 6 months postoperatively, and Oswestry Disability Index at postoperative 6 months were recorded. Age, sex and modified Charlson Comorbidity Index were analyzed by linear regression. The correlation of BMI with revision rate was evaluated by multivariate Cox proportional hazards model.

RESULTS AND CONCLUSION: (1) The treatment outcomes of MIS-TLIF were satisfactory. (2) The postoperative low back pain Visual Analogue Scale scores were significantly improved, and the postoperative scores and Oswestry Disability Index showed no significant differences among groups. (3) Increasing BMI manifested association with more preoperative comorbidities (P=0.001) and longer operation time (P=0.000). (4) Cox proportional hazards model revealed that increasing BMI was not the independent risk factor for revision rate following MIS-TLIF (P=0.299). (5) Our results indicate that increasing BMI is not a risk factor for revision procedures within 2 years after MIS-TLIF. Therefore, surgeons need not be anxious about high BMI patients after MIS-TLIF for its potential high revision rate.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Body Mass Index, Surgical Procedures, Minimally Invasive, Spinal Fusion, Tissue Engineering

CLC Number:

R318

Xu Li-chen, Xu Wei-bing, Yang Dong-fang, Zhang Hai-bin. Transforaminal lumbar interbody fusion for degenerative disc diseases: relationship between body mass index and revision rate [J]. Chinese Journal of Tissue Engineering Research, 2018, 22(19): 2994-2999.

Figures/Tables 2

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