中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (38): 7153-7156.doi: 10.3969/j.issn.1673-8225.2011.38.029

• 组织工程口腔材料 tissue-engineered oral materials • 上一篇    下一篇

口腔组织补片预防腮腺术后味觉出汗综合征

黄代营1，李  祥2，聂二民1，郭  冰1   

  1. 1中山大学附属第一医院口腔科，广东省广州市  510080
    2中山大学附属第一医院黄埔院区口腔科 广东省广州市   510700
  • 收稿日期:2010-12-22 修回日期:2011-02-17 出版日期:2011-09-17 发布日期:2011-09-17
  • 通讯作者: 郭 冰，硕士，副教授，中山大学附属第一医院口腔科，广东省广州市 510080
  • 作者简介:黄代营★，男，1966年生，湖北省宜昌市人，汉族，2003年中山大学毕业，硕士，主治医师，主要从事口腔颌面外科学方面研究。 niean_1999@163.com
  • 基金资助:

    广东省科技计划项目(2009B030801097)课题名称：计算机辅助颌面外科手术设计与导向系统的开发应用研究。

HEAL-ALL tissue patch in prevention of Frey syndrome after parotidectomy

Huang Dai-ying1, Li Xiang2, Nie Er-min1, Guo Bing1   

  1. 1Department of Stomatology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou  510080, Guangdong Province, China
    2Department of Stomatology, the Huangpu Branch of the First Affiliated Hospital of Sun Yat-sen University, Guangzhou  510700, Guangdong Province, China
  • Received:2010-12-22 Revised:2011-02-17 Online:2011-09-17 Published:2011-09-17
  • Contact: Guo Bing, Master, Associate professor, Department of Stomatology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China niean_1999@163.com
  • About author:Huang Dai-ying★, Master, Attending physician, Department of Stomatology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China niean_1999@163.com
  • Supported by:

    the Social Development Project of Guangdong Provincial Science and Technology Department, No. 2009B030801097*

PDF

342

被引次数

7

摘要：

背景：近年来，脱细胞真皮基质的应用对于预防味觉出汗综合征取得较满意的临床效果。
目的：评价腮腺浅叶或部分切除后，采用HEAL-ALL(海奥)口腔组织补片植入腮腺咬肌筋膜和剩余腮腺组织之间，预防味觉出汗综合征的效果。
方法：选择腮腺良性肿瘤患者84例，分为2组。实验组在行腮腺浅叶或部分切除后，于腮腺咬肌筋膜和剩余腮腺组织之间植入组织补片；对照组按常规行腮腺浅叶或部分切除。术后通过电话回访对味觉出汗综合征发生情况评估，并且随机各抽取30例进行面部碘-淀粉试验。
结果与结论：电话回访：实验组1例、对照组27例出现味觉出汗综合征症状。碘-淀粉试验味觉出汗综合征发生率：实验组阳性2例，对照组阳性22例(P < 0.01)。提示腮腺浅叶或部分切除后，植入HEAL-ALL(海奥)口腔组织补片有预防味觉出汗综合征的作用。

关键词: 腮腺良性肿瘤, HEAL-ALL组织补片, 腮腺切除术, Frey综合征, 口腔组织补片

Abstract:

BACKGROUND: Recently, great achievements of acellular dermal matrix which is used to prevent Frey syndrome have been reported.
OBJECTIVE: To evaluate the role of oral tissue patch (HEAL-ALL) in preventing Frey syndrome after parotidectomy.
METHODS: Eighty-four patients were divided into two groups. Thirty-five patients of groupⅠwho received a superficial lobe parotidectomy and oral tissue patches were put between the fascia parotidea masseterica flap and the remaining parotid tissue. Group 2 consisted of 49 patients who underwent the parotidectomy. All patients were evaluated for gustatory sweating by identical phone. Sixty randomly chosen patients (group Ⅰ30, group Ⅱ30) were evaluated using the Minor Starch Iodine Test (MSIT).
RESULTS AND CONCLUSION: The responses to phone showed presence of Frey syndrome in 1 of 30 in groupⅠ, whereas group Ⅱ showed 27 of 49 patients presented with Frey syndrome. The objective results test by those who underwent the MSIT revealed a 6.67% (2) and 73.33% (22) incidence of Frey syndrome in groupsⅠ and Ⅱ, respectively. There was significant difference between the two groups (P < 0.01). HEAL-ALL tissue patch is shown to be an effective way for preventing Frey syndrome post-parotidectomy.

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