中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (29): 5409-5412.doi: 10.3969/j.issn.1673-8225.2011.29.022

• 组织工程口腔材料 tissue-engineered oral materials • 上一篇    下一篇

HEAL-ALL组织补片在拔牙后干槽症预防中的应用

黄代营，聂二民，郭俊兵，吉  利   

  1. 中山大学附属第一医院口腔科，广东省广州市   510080
  • 收稿日期:2011-01-11 修回日期:2011-02-17 出版日期:2011-07-16 发布日期:2011-07-16
  • 通讯作者: 吉利，硕士，主治医师，中山大学附属第一医院口腔科，广东省广州市 510080
  • 作者简介:黄代营★，男，1966年生，湖北省宜昌市人，汉族，2003年中山大学毕业，硕士，主治医师，主要从事口腔颌面外科学方面研究。 niean_1999@163.com
  • 基金资助:

    广东省科技计划项目(2008B060600018)，课题名称：双维控制的垂直牙槽骨牵张器的研制及动物实验。

Application of the HEAL-ALL tissue patch on the prevention of dry socket syndrome after tooth extraction

Huang Dai-ying, Nie Er-min, Guo Jun-bing, Ji Li   

  1. Department of Stomatology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou  510080, Guangdong Province, China
  • Received:2011-01-11 Revised:2011-02-17 Online:2011-07-16 Published:2011-07-16
  • Contact: Ji Li, Master, Attending physician, Department of Stomatology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China
  • About author:Huang Dai-ying★, Master, Attending physician, Department of Stomatology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China niean_1999@163.com
  • Supported by:

    Science and Technology Planning Project of Guangdong Province, China, No. 2008B060600018*

PDF

613

被引次数

22

摘要：

背景：口腔组织补片是将异体组织经过脱细胞处理后的一种细胞外基质，具有组织相容性好、来源充分、易操作的特性，在口腔颌面外科领域应用广泛。
目的：将HEAL-ALL(海奥)口腔组织补片植入下颌阻生牙拔除后牙槽窝，评价其预防干槽症的效果。
方法：选择中山大学附属第一医院口腔外科门诊拔除下颌阻生牙的患者80例，随机分成2组，试验组在拔除阻生牙后放入HEAL-ALL(海奥)组织补片，对照组不放任何材料任其自行愈合，1周后复诊观察干槽症的发生情况。
结果与结论：试验组无干槽症发生，对照组有6例干槽症发生，两组干槽症发生率的差异有显著性性意义(P < 0.05)。提示对于复杂阻生牙拔除，损伤大、操作时间长的患者，为了预防其干槽症的发生，建议术后采用组织补片填入牙槽窝的方法。

关键词: 阻生牙, HEAL-ALL组织补片, 并发症, 干槽症, 口腔生物材料

Abstract:

BACKGROUND: Oral tissue patch is a kind of extracellular matrix that allograft tissue treated by decellularized treatment, which has a good histocompatibility, sufficient resource and simple operation, and has been widely used in oral and maxillary surgery.
OBJECTIVE: To evaluate the effect of HEAL-ALL tissue patch on the prevention of dry socket syndrome after tooth extraction
METHODS: A total of 80 patients who had been extracted mandibular third molar were selected in the First Affiliated Hospital of Sun Yat-sen University, which were randomly divided into 2 groups. In the experimental group, oral tissue patches were put into the sockets after mandibular third molars were extracted, while in the control group, we let the wounds to be healed naturally without any materials. The incidence of dry socket syndrome was observed after 1 week.
RESULTS AND CONCLUSION: No patient had dry socket after operation in the experimental group, but in the control group, 6 patients suffered from dry socket. There was a significant difference in the incidence between the two groups (P < 0.05). In order to prevent the incidence of dry socket, especially in very difficult cases which are more traumatic and time-consuming, it is a good choice to put the oral tissue patch into socket after operation to prevent dry socket.

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