中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (20): 3797-3800.doi: 10.3969/j.issn.1673-8225.2011.20.046

• 组织构建临床实践 clinical practice in tissue construction • 上一篇    

新疆多民族地区出生缺陷分析

钱若筠1，刘  红2，钟  南3，王  瑞4，邹红云4，何  江4，余伍忠4   

  1. 1解放军兰州军区乌鲁木齐总医院麻醉手术科，新疆维吾尔自治区乌鲁木齐市  830000
    2新疆医科大学第六附属医院，新疆维吾尔自治区乌鲁木齐市  830002
    3北京大学医学部医学遗传学系，北京市  100191
    4解放军兰州军区乌鲁木齐总医院临床医学研究所，新疆维吾尔自治区乌鲁木齐市  830000
  • 收稿日期:2010-10-26 修回日期:2010-12-15 出版日期:2011-05-14 发布日期:2011-05-14
  • 通讯作者: 余伍忠，硕士，副主任技师，解放军兰州军区乌鲁木齐总医院临床医学研究所，新疆维吾尔自治区乌鲁木齐市 830000
  • 作者简介:钱若筠★，女，1962年生，江苏省无锡市人，汉族，2001年新疆医科大学毕业，硕士，主任医师，主要从事临床麻醉方面的研究。

Analysis of birth defects in Xinjiang multi-ethnic region

Qian Ruo-yun1, Liu Hong2, Zhong Nan3, Wang Rui4, Zou Hong-yun4, He Jiang4, Yu Wu-zhong4   

  1. 1Department of Anesthesiology, Urumqi General Hospital of Lanzhou Area Command of Chinese PLA, Urumqi  830000, Xinjiang Uighur Autonomous Region, China
    2Sixth Hospital of Xinjiang Medical University, Urumqi  830002, Xinjiang Uighur Autonomous Region, China
    3Department of Medical Genetics, Peking University Health Science Center, Beijing  100191, China
    4Institute of Clinical Medicine, Urumqi General Hospital of Lanzhou Area Command of Chinese PLA，Urumqi  830000, Xinjiang Uighur Autonomous Region, China
  • Received:2010-10-26 Revised:2010-12-15 Online:2011-05-14 Published:2011-05-14
  • Contact: Yu Wu-zhong, Master, Associate chief technician, Institute of Clinical Medicine, Urumqi General Hospital of Lanzhou Area Command of Chinese PLA，Urumqi 830000, Xinjiang Uighur Autonomous Region, China wuzhong.yu@yahoo.com.cn
  • About author:Qian Ruo-yun★, Master, Chief physician, Department of Anesthesiology, Urumqi General Hospital of Lanzhou Area Command of Chinese PLA, Urumqi 830000, Xinjiang Uighur Autonomous Region, China ruoyunq@sina.com

PDF

379

被引次数

5

摘要：

背景: 新疆是一个多民族聚居的省区，地理位置不同，经济条件、气候环境等差异较大。
目的：了解新疆不同民族出生缺陷发生发展趋势、病种及民族和地区差异。
方法：根据新疆特殊的民族、地理条件及经济状况，按随机分层整群抽样方法，确定13个县(市)作为监测点，使用《中国出生缺陷监测方案》填报《出生缺陷儿登记卡》和《围产儿情况季报表》。出生缺陷的诊断采用ICD10诊断标准。对2005-01/2008-12 4年间出生缺陷发生率进行统计，并分析出生缺陷的病种及其在各民族、地区的分布情况。
结果与结论：新疆地区出生缺陷的平均发生率为97.43/万，4年间出生缺陷发生率表现为2006年较上一年度显著降低后，随之又逐年上升。出生缺陷发生率农村高于城市，男性多于女性，天山以南地区高于天山以北、以东及乌鲁木齐地区。在新疆的主要民族中，出生缺陷发生率以锡伯族和维吾尔族最高，满族和哈萨克族次之，汉族最低。4年间满族、蒙古族、回族出生缺陷发生率逐年下降，维吾尔族、汉族和哈萨克族有较小波动；但锡伯族却经历了一次大起大落的变化。出生缺陷病种前5位依次为神经管畸形、总唇裂、无脑畸形、先天性脑积水、唇裂合并腭裂。从分析结果可以看出新疆地区出生缺陷的发生存在民族和地理差异。

关键词: 出生缺陷, 发生率, 围产儿, 监测, 变化趋势

Abstract:

BACKGROUND: Xinjiang is a multi-ethnic region with significant differences in local geographical position, economic development and climatic environment.
OBJECTIVE: To analyze the occurrence and development tendency of birth defects, disease categories and disparity among different ethnic groups and regions in Xinjiang.
METHODS: A stratified cluster random sampling observation was performed in 13 counties (cities) according to the status of ethnical distribution and local economics of Xinjiang. Quarter Report Sheet on Babies and The defect babies register card were filled as the scheme of Chinese birth defect monitoring, and ICD10 diagnostic code was adopted in birth defect diagnosis. The birth defects rate was calculated from January 2005 to December 2008, and the disease categories and disparity among different ethnic groups and regions in Xinjiang were analyzed.  
RESULTS AND CONCLUSION: The average incidence rate of birth defect was 9.74‰, which was dramatically descended in 2006 and ascended afterward yearly. The incidence rate of countryside was higher than city, and male more than female. In geography, south of Tianshan Mountain was higher than north and east in birth defect incidence. Among major ethnic groups in Xinjiang, Sibe and Uygur had the highest birth defect incidence rate, followed by Man, Hazakh, and Han. The birth defect incidence of Han, Uygur and Hazakh people showed descend tendency, Hui, Mongolia, and Man people fluctuated, yet Sibe’s rate had a change of rise and fall. The first five birth defect entities were neural tube deformity, cleft lips, anencephaly, congenital hydrocephalus and cleft palate combined with cleft lips. The birth defects rates are different from ethnic groups and regions in Xinjiang.

中图分类号: