中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (19): 3594-3597.doi: 10.3969/j.issn.1673-8225.2011.19.042

• 干细胞学术探讨 stem cell academic discussion • 上一篇    下一篇

中药促进间充质干细胞的增殖与分化

王艳春1，2，曲  静1，韩雅玲2   

  1. 1辽宁中医药大学，辽宁省沈阳市  110032
    2解放军沈阳军区总医院，辽宁省沈阳市 110840
  • 收稿日期:2011-02-18 修回日期:2011-04-10 出版日期:2011-05-07 发布日期:2011-05-07
  • 通讯作者: 韩雅玲，博士，教授，主任医师，解放军沈阳军区总医院，辽宁省沈阳市110840
  • 作者简介:王艳春☆，男，1974年生，辽宁省沈阳市人，汉族，2011年辽宁中医药大学毕业，博士，主治医师，主要从事中西医结合心血管病专业方面的研究。 w20090807@qq.com

Traditional Chinese medicine promotes proliferation and differentiation of mesenchymal stem cells

Wang Yan-chun1,2, Qu Jing1, Han Ya-ling2   

  1. 1Liaoning University of Traditional Chinese Medicine, Shenyang  110032, Liaoning Province, China
    2General Hospital of Shenyang Military Area Command, Shenyang  110840, Liaoning Province, China
  • Received:2011-02-18 Revised:2011-04-10 Online:2011-05-07 Published:2011-05-07
  • Contact: Han Ya-ling, Doctor, Professor, Chief physician, General Hospital of Shenyang Military Area Command, Shenyang 110840, Liaoning Province, China
  • About author:Wang Yan-chun☆, Doctor, Attending physician, Liaoning University of Traditional Chinese Medicine, Shenyang 110032, Liaoning Province, China; General Hospital of Shenyang Military Area Command, Shenyang 110840, Liaoning Province, China w20090807@qq.com

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摘要：

背景：间充质干细胞是再生医学研究的热点，中药干预间充质干细胞为再生医学的研究注入了新的活力。
目的：回顾与总结近年来间充质干细胞研究过程中加入中药干预的研究，旨在进一步探索中医药与间充质干细胞研究的结合点和发展趋势。
方法：以“中药”或“中草药”和“间充质干细胞”为检索词，检索CNKI数据库，以 “traditional Chinese medicine”或“herbal medicine”或“Botanical Drugs”和“mesenchymal stem cells” 为检索词检索Pubmed医学数据库。
结果与结论：检索到符合纳入标准的文献共35篇。结果显示许多中药及复方对间充质干细胞增殖与分化有促进作用，具有安全、易于在临床推广使用等特点。而且中药在间充质干细胞体内存活等方面具有重大潜力。

关键词: 中药, 间充质干细胞, 诱导分化, 增殖, 文献综述

Abstract:

BACKGROUND: Mesenchymal stem cells are the hotspot in regenerative medicine research, and traditional Chinese medicine (TCM) can improve the efficacy of mesenchymal stem cells therapy.
OBJECTIVE: To review the correlation between TCM and stem cells, and to further explore their development trend.
METHODS: A computer retrieve of CNKI and PubMed databases using the key words of which were “traditional Chinese medicine” or “herbal medicine” or “Botanical Drugs” and “mesenchymal stem cells” in Chinese and English was performed.
RESULTS AND CONCLUSION: Totally 35 articles were included. The results showed that many Chinese herbs and compound play a role in improving the proliferation and differentiation of mesenchymal stem cells, which is safe and easy to clinical application. In addition, Chinese herbs have a great potential to survive in mesenchymal stem cells.

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