中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (35): 6540-6543.doi: 10.3969/j.issn.1673-8225.2010.35.020

• 骨与关节图像与影像 bone and joint imaging • 上一篇    下一篇

多层螺旋CT与虚拟结肠镜在猪肠道重建中的应用

张  斌1，朱  铭2，邱海盛2   

  1. 上海交通大学医学院附属上海儿童医学中心，1消化科，2放射科，上海市  200127
  • 出版日期:2010-08-27 发布日期:2010-08-27
  • 通讯作者: 朱铭，博士生导师，上海交通大学医学院附属上海儿童医学中心放射科，上海市 200127
  • 作者简介:张斌★，男，1976年生，上海市人，汉族，2008年上海交通大学医学院毕业，硕士，主治医师，主要从事消化科方面的研究。 dr8164@126.com

Multi-slice spiral CT and virtual endoscopy in reconstruction of pig intestinal tract

Zhang Bin1, Zhu Ming2, Qiu Hai-sheng2   

  1. 1 Department of Digestion, 2 Department of Radiology, Shanghai Children’s Medical Center, Shanghai Jiao Tong University, Shanghai  200127, China
  • Online:2010-08-27 Published:2010-08-27
  • Contact: Zhu Ming, Doctoral supervisor, Department of Radiology, Shanghai Children’s Medical Center, Shanghai Jiao Tong University, Shanghai 200127, China
  • About author:Zhang Bin★, Master, Attending physician, Department of Digestion, Shanghai Children’s Medical Center, Shanghai Jiao Tong University, Shanghai 200127, China dr8164@126.com

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被引次数

1

摘要：

背景：在不影响检查结果的基础下合理降低CT扫描剂量是以后的发展趋势。低扫描剂量CT肠道重建是否可行是近年来探讨研究的热点。
目的：探讨低剂量扫描在多层螺旋CT肠道重建中的可行性。
方法：选用新鲜离体猪结肠制作36枚息肉模型。按设置参数不同随机分为3组：150 mA，100 mA， 50 mA。采用GE LightSpeed16排螺旋CT扫描。每组肠段均行3个角度扫描，即猪结肠纵轴与扫描架平面成0°，45°，90°扫描。在工作站上用仿真内镜技术进行肠道重建，根据图像诊断结果比较3组对息肉的灵敏度。
结果与结论：36枚息肉在150 mA，100 mA， 50 mA扫描强度下分别检出36枚，35枚，33枚，各自的灵敏度分别为100%，97.2%，91.7%，组间差异无显著性意义(P=0.162)。在0°，45°，90°不同扫描角度下检出的猪结肠息肉数分别为34枚，34枚，36枚，各自的灵敏度分别为94.4%，94.4%，100%，组间差异无显著性意义(P=0.354)。提示低剂量多层螺旋CT肠道重建图像可提供足够的诊断信息，可满足仅单纯查看结肠息肉的诊断需要。多层螺旋CT以50 mA的管电流扫描剂量遵循了X射线正当化，防护最优化的原则，在放射剂量和图像质量之间可以很好地建立平衡。

关键词: 结肠, 息肉模型, 多层螺旋CT, 仿真内窥镜, 数字化医学

Abstract:

BACKGROUND: Appropriate reduction of CT scanning dose while not influencing examination is the trend in future. Low dose CT intestinal tract reconstruction has become a focus in recent studies.
OBJECTIVE: To explore the feasibility of low dose multi-slice CT (MSCT) scan in reconstruction of intestinal tract.
METHODS: Fresh colons of pigs were made into 36 polyps moulds and randomly divided into 150 mA, 100 mA and 50 mA groups. All pieces of colon underwent MSCT scanning with the angle of 0°, 45° and 90° to the gantry. Intestinal tract was reconstructed using virtual endoscopy and the sensitivity was calculated.
RESULTS AND CONCLUSION: The number of polyps that was detected by low dose MSCT were 36 polyps for 150 mA group, 35 polyps for 100 mA group and 33 polyps for 50 mA group with diagnostic sensitivity 100%, 97.2% and 91.7% (P=0.162). The number of detection was 34 polyps for 0° group, 34 polyps for 45° group and 36 polyps for 90° group with diagnostic sensitivity 94.4%, 94.4% and 100% (P=0.354). The reconstruction of low dose MSCT could offer sufficient information for diagnosis and satisfy the diagnose requirement of colon polypous. Tube current of 50 mA follows the principle of legalisation and optimizing shelter of X ray and establish balance between radiation dosage and picture quality.

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