中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (28): 5276-5280.doi: 10.3969/j.issn.1673-8225.2010.28.035

• 组织构建学术探讨 tissue construction academic discussion • 上一篇    下一篇

无症状型颈椎退变对脊髓的压迫

张连记   

  1. 山东省定陶县人民医院骨科，山东省菏泽市 274100 
  • 出版日期:2010-07-09 发布日期:2010-07-09
  • 作者简介:张连记，男，1968年生，山东省定陶县人，汉族，1990年山东中医药大学骨伤系毕业，副主任医师，主要从事颈肩腰腿痛的研究。 zhanglianji123@163.com

Asymptomatic spondylotic cervical cord compression 

Zhang Lian-ji   

  1. Department of Orthopaedics, Dingtao County People’s Hospital, Heze   274100, Shandong Province, China
  • Online:2010-07-09 Published:2010-07-09
  • About author:Zhang Lian-ji, Associate chief physician, Department of Orthopaedics, Dingtao County People’s Hospital, Heze 274100, Shandong Province, China zhanglianji123@163.com

PDF

558

被引次数

4

摘要：

背景：目前对无症状颈椎退变性脊髓压迫的影像现象尚缺乏系统研究和认识。
目的：探讨无症状颈椎退变性脊髓压迫的临床特点及治疗方法。
方法：以“无症状、颈椎、退变性脊髓压迫、组织工程”为中文检索词。以“asymptomatic spondylotic cervical cord compression”为英文检索词，应用计算机检索PubMed、万方数据库及重庆维普(VIP)期刊全文数据库1987-01/2009-01文献并查阅有关图书资料。纳入有关无症状颈椎退变性脊髓压迫的临床文献。排除重复性研究和不典型报道。保留36篇文献做进一步分析。
结果与结论：无临床症状和体征的颈椎退变所形成的致压物对脊髓压迫的MRI征象上，发现脊髓压迫而不具备脊髓型颈椎病的症状和体征者诊断为无症状压迫；临床治疗方法的评价没有统一的标准。因此制定一个统一的评判标准，将有利于临床准确诊断分型及临床疗效的评估和疗法的选择，从而选择出最佳治疗方案，以提高疗效和稳定性。动物实验表明，将组织工程同种异体冻干辐照骨应用于椎板切除术后椎板重建，发现其在引导推板再生，预防全椎板切除后并发症方面效果较为满意。

关键词: 退变性脊髓压迫, 无症状, 颈椎, 骨组织工程, 椎板重建

Abstract:

BACKGROUND: Image research has been less reported about asymptomatic spondylotic cervical cord compression.
OBJECTIVE: To explore the clinical characteristics and treatment method of asymptomatic spondylotic cervical cord compression.
METHODS: Articles were retrieved from PubMed, Wanfang database, and VIP database with the key words of “asymptomatic spondylotic cervical cord compression” in both English and Chinese between January 1987 and January 2009. Clinical references related to asymptomatic spondylotic cervical cord compression were included, but duplicated research and untypical reports were excluded. A total of 36 articles were included in the final analysis.
RESULTS AND CONCLUSION: MRI demonstrated that patients who did not have symptoms and signs of cervical spondylotic myelopathy were diagnosed as asymptomatic compression. Standard criteria should be set to exactly determine clinical diagnosis and evaluate therapeutic effect; thereby the best treatment method is chosen to improve therapeutic effect and stability. Animal experiment demonstrated that tissue-engineered allogeneic freeze-drying radiation bone satisfactorily introduced vertebral plate regeneration, prevented complication following intact vertebral plate resection.

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