中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (25): 4653-4656.doi: 10.3969/j.issn.1673-8225.2010.25.023

• 组织工程口腔材料 tissue-engineered oral materials • 上一篇    下一篇

牙周炎治疗前后口腔挥发性硫化物质量浓度变化的便携式气相色谱仪检测

张盛炎1，杨军英1，陈  珊1，王小燕2   

  1. 1中山大学附属第一医院口腔科，广东省广州市    510080；2武装警察部队广东总队医院口腔科，广东省广州市    510507
  • 出版日期:2010-06-18 发布日期:2010-06-18
  • 通讯作者: 杨军英，硕士，副主任医师，中山大学附属第一医院口腔科，广东省广州市 510080 aliceyang2006@126.com
  • 作者简介:张盛炎★，男，1980年生，广东省广州市人，汉族，2007年中山大学毕业，硕士，医师，主要从事口腔内科方面的研究。 shengyan_4444@yahoo.com.cn
  • 基金资助:

    课题受广东省科学技术厅社会发展项目“牙周治疗对合并牙周病的冠心病的作用”(2007B031500018)资助。

Concentration changes of oral volatile sulfur compounds before and after periodontal treatment with a portable gas chromatography

Zhang Sheng-yan1, Yang Jun-ying1, Chen Shan1, Wang Xiao-yan2   

  1. 1 Department of Stomatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou   510080, Guangzhou Province, China; 2 Department of Stomatology, Guangdong Armed Police General Hospital, Guangzhou   510507, Guangzhou Province, China
  • Online:2010-06-18 Published:2010-06-18
  • Contact: Yang Jun-ying, Master, Associate chief physician, Department of Stomatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, Guangzhou Province, China aliceyang2006@126.com
  • About author:Zhang Sheng-yan★, Master, Physician, Department of Stomatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, Guangzhou Province, China shengyan_4444@yahoo.com.cn
  • Supported by:

     Social Development Program of Guangdong Provincial Science and Technology Ministry, No. 2007B031500018*

PDF

360

被引次数

6

摘要：

背景：口气中挥发性硫化物是近年来牙周病学的研究热点。目前，有关牙周治疗对挥发性硫化物3种主要成分质量浓度影响的报道较少。
目的：采用便携式气相色谱仪(OralChroma™)检测牙周炎患者口腔挥发性硫化物的质量浓度变化。
方法：采用鼻闻法评定口臭值筛选出全身健康牙周炎患者40例，应用便携式气相色谱仪(OralChroma™)测定牙周基础治疗前及治疗后1周牙周炎患者口气挥发性硫化物中3种主要成分气体(硫化氢、甲基硫醇和二甲基硫)的质量浓度。牙周治疗包括龈上洁治、龈下刮治和根面平整及牙周冲洗。
结果与结论：牙周基础治疗后患者牙周状况得到改善，口气中挥发性硫化物质量浓度显著降低(P < 0.01)，其中硫化氢、甲基硫醇的质量浓度降幅> 80%，二甲基硫质量浓度降幅>50%，硫化氢在3种气体中的质量浓度最高(P < 0.01)。牙周治疗后口臭值显著低于治疗前(P < 0.01)。提示便携式气相色谱仪能有效检测口腔挥发性硫化物的主要成分和质量浓度变化，准确反映口臭程度的改变。牙周治疗是减轻牙周炎患者口臭程度和降低口气中挥发性硫化物质量浓度的有效方法。

关键词: 口臭, 牙周炎, 挥发性硫化物, 牙周治疗, 气相色谱法

Abstract:

BACKGROUND: The volatile sulfur compounds (VSCs) is the hotspot in recent years of periodontitis research. There have been few related studies concentrating on the change of three main components of the VSCs by periodontal treatment.
OBJECTIVE: To evaluate the changes of VSCs levels in periodontitis patients before and after periodontal treatment by using a portable gas chromatography.
METHODS: Forty patients with periodontitis in good healthy state were selected according to the organoleptic rating. The levels of three major components of VSCs (H2S, CH3SH, (CH3)2S) were measured before and after periodontal treatment with a portable gas chromatography (OralChroma™). The periodontal therapy includes supragingival scaling, subgingival scaling, root planing and periodontal rinsing.
RESULTS AND CONCLUSION: The periodontal treatment could improve the periodontal conditions of periodontitis patients and significantly reduce the levels of VSCs (P < 0.01). The levels of H2S and CH3SH were reduced by more than 80% and (CH3)2S by more than 50%. H2S had the highest levels among three kinds of gases (P < 0.01). There was a significant reduction of organoleptic rating scores after periodontal treatment compared with before treatment (P < 0.01). A portable gas chromatography can effectively measure the components and concentration of the VSCs, and accurately detect the changes of halitosis. Periodontal treatment is an effective treatment to reduce oral malodour and VSCs levels.

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