中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (22): 4123-4126.doi: 10.3969/j.issn.1673-8225.2010.22.034

• 骨与关节临床实践 clinical practice of the bone and joint • 上一篇    下一篇

椎体成形治疗胸腰椎压缩性骨折影响因素的多元回归分析：与置入物固定、器械种类、伤椎节段有关吗？

孙建忠1，马  台1，丁  任1，石关桐1，傅  强2，侯铁胜2   

  1. 1上海市宝山区中心医院骨科，上海市  201900；   2解放军第二军医大学长海医院骨科，上海市 200433
  • 出版日期:2010-05-28 发布日期:2010-05-28
  • 通讯作者: 傅 强，副教授，副主任医师，硕士生导师，解放军第二军医大学长海医院骨科，上海市 200433 Johson.f@163. com
  • 作者简介:孙建忠★，男，1981年生，山东省鄄城市人，汉族，2009年解放军第二军医大学毕业，硕士，医师，主要从事脊柱外科的研究。 sunjianzhongsjz@163.com

Multiple regression analysis on influential factors of vertebroplasty in the treatment of thoracolumbar vertebral compression fractures: Are they correlated with implant fixation, instrument types, and vertebral segment?

Sun Jian-zhong1, Ma Tai1, Ding Ren1, Shi Guan-tong1, Fu Qiang2, Hou Tie-sheng2   

  1. 1 Department of Orthopedics, Baoshan Central Hospital, Shanghai  201900, China; 2 Department of Orthopedics, Changhai Hospital, Second Military Medical University, Shanghai   200433, China
  • Online:2010-05-28 Published:2010-05-28
  • Contact: Fu Qiang, Associate professor, Associate chief physician, Master’s supervisor, Department of Orthopedics, Changhai Hospital, Second Military Medical University, Shanghai 200433, China Johson.f@163.com
  • About author:Sun Jian-zhong★, Master, Physician, Department of Orthopedics, Baoshan Central Hospital, Shanghai 201900, China sunjianzhongsjz@ 163.com

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摘要：

背景：目前椎体成形在脊柱外科应用日益广泛，疗效显著，但国内外文献对其影响因素的报道很少，仅有少量对单个因素的研究。
目的：对22个可能因素进行分析，旨在寻找影响椎体成形治疗胸腰椎压缩性骨折愈后的因素，建立多元线性回归方程。
方法：采用门诊复查方式有效随访到61例椎体成形患者，平均随访17个月，由两名脊柱外科医生对患者进行治疗前后目测类比评分，结果采用两人评分的平均值。由患者自行填写影响因素信息表，应用SAS 9.1.3统计学软件分析影响因素与椎体成形前后目测类比评分的关系。
结果与结论：椎体成形治疗各种性质胸腰椎骨折疗效显著；椎体成形后疗效与伤椎节段、病程、器械种类、是否内固定有关；建议使用Sky产品；椎体成形同时应该合理选用椎弓根钉棒系统内固定，把握好手术适应证，能不行内固定尽量不用；及早发现骨折并早期治疗。

关键词: 椎体成形, 椎体压缩性骨折, 内固定, 影响因素, 多元线性回归

Abstract:

BACKGROUND: Vertebroplasty is used widely in spinal surgery, and its effect is favorable. There are few reports on the influential factors, and only a small amount of individual factors are discussed.
OBJECTIVE: To analyze 22 possible factors to find factors that affect vertebroplasty treatment of thoracolumbar compression fracture, and to establish the multiple linear regression equation.
METHODS: A total of 61 patients with vertebral compression fractures were followed up for an average time of 17 months. The visual analog scale (VAS) scores of patients were determined before and after treatment, and the average value of each patient was obtained. The patients were interviewed to assess treatment results. Relationship between influential factors and VAS was analyzed using SAS9.1.3 software.
RESULTS and CONCLUSION: The treatment effect of vertebroplasty was positive. The outcome of the vertebroplasty surgery was correlated with the course of the disease, the characteristics of the used surgery instruments and internal fixation treatment. Sky instruments were better than Kyphon ones. Moreover, appropriate internal fixation using pedicle screw system, operation indications, and early diagnosis and treatment of vertebral compression fractures are highlighted in vertebroplasty.

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