Measurement of paravertebral muscle indicators on MRI in the patients with osteoporotic vertebral fracture and its clinical significance

doi:10.3969/j.issn.2095-4344.1040

Abstract

Abstract:

BACKGROUND: Etiology of osteoporotic vertebral fracture is a combination of multiple factors. Bone loss, falls and previous fracture history are considered to be the main risk factors, but the specific pathogenesis remains to be further studied.

OBJECTIVE: To measure the indicators of paravertebral muscles on MRI in patients with osteoporotic vertebral fracture and to investigate its correlation with the occurrence of vertebral fracture.

METHODS: Ninety-five patients with osteoporotic vertebral fracture patients and with complete clinical data admitted in Hunan Provincial People’s Hospital from June 2014 to December 2017 were enrolled. The cross sectional area of paravertebral muscles and the fatty degeneration ratio were examined and assessed through MRI. The measurement parameters were as follows: the cross sectional area of bilateral multifidi and erector spinae, the cross sectional area of vertebral body, the degree of lumbar vertebrae muscles, and the fatty degeneration ratio. The fracture group was divided into single fracture and multiple fracture groups according to the number of fractured vertebrae. Meanwhile, 32 osteoporosis patients without fracture were enrolled as control group. Independent sample t test was used to compare the differences in the MRI indicators of the paravertebral muscles in the three groups.

RESULTS AND CONCLUSION: (1) Compared with the control group, the cross sectional areas of bilateral multifidi and erector spinae in the single fracture and multiple fracture groups were decreased significantly (P < 0.05). There was no significant difference between two fracture groups (P > 0.05). (2) There was no significant difference in the cross sectional area of vertebral body between two groups (P > 0.05). (3) Compared with the control group, the degree of lumbar vertebrae muscles in the single fracture and multiple fracture groups was significantly reduced (P < 0.05). However, there was no significant difference between two fracture groups (P > 0.05). (4) The fatty degeneration ratio in the multiple fracture group was significantly higher than that in the control group (P < 0.05). There was no significant difference among the other groups (P > 0.05). (5) In summary, the number and quality of the paravertebral muscles in the patients with osteoporotic vertebral fracture are lower than those in the osteoporotic patients without fracture, suggesting that the degeneration of lumbar paravertebral muscles may be a potential risk factor for osteoporotic vertebral fracture.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Lumbar Vertebrae, Osteoporotic Fractures, Magnetic Resonance Imaging, Tissue Engineering

CLC Number:

R445

Liu Bin, Liu Xiangyang, Wang Guoping, Shen Xiongjie, Chang Lei, Peng Shuai, Zhang Mingyan. Measurement of paravertebral muscle indicators on MRI in the patients with osteoporotic vertebral fracture and its clinical significance [J]. Chinese Journal of Tissue Engineering Research, 2019, 23(4): 578-583.

Figures/Tables 2

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