Chinese Journal of Tissue Engineering Research ›› 2019, Vol. 23 ›› Issue (4): 512-517.doi: 10.3969/j.issn.2095-4344.1031

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Multiple posterior lumbar interbody fusion and posterolateral fusion instrumentation for thoracolumbar kyphosis and osteoporotic fracture in older adults  

Li Qingsong1, 2, Liu Shaoyu3, Yin Zongsheng1   

  1. 1Department of Orthopedics, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China; 2Department of Spinal Surgery, Anhui No. 2 Provincial People’s Hospital, Hefei 230011, Anhui Province, China; 3Department of Spinal Surgery, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China
  • Online:2019-02-08 Published:2019-02-08
  • Contact: Yin Zongsheng, MD, Professor, Chief physician, Department of Orthopedics, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China
  • About author:Li Qingsong, Attending physician, Department of Orthopedics, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China; Department of Spinal Surgery, Anhui No. 2 Provincial People’s Hospital, Hefei 230011, Anhui Province, China

Abstract:

BACKGROUND: With aged trend of population in China becoming severe, the incidence of osteoporosis fracture with thoracolumbar kyphosis is increasing. Whether osteotomy is required or not still remains a controversy.

OBJECTIVE: To evaluate the clinical efficacy and improvement in sagittal vertical axis after multiple posterior lumber interbody fusion and posterolateral fusion instrumentation for patients with osteoporotic fracture with thoracolumbar kyphosis.
METHODS: Totally 90 cases of senile osteoporosis were included in the retrospective study. Operation group included 40 patients suffering osteoporosis and thoracolumbar kyphosis who underwent anti-osteoporosis treatment and multilevel posterior lumbar interbody fusion and posterolateral fusion instrumentation. Control group included 50 patients with osteoporotic without kyphosis. The Oswestry Disability Index and Visual Analogue Scale scores were compared between two groups after follow-up. Spinoplevic parameters, such as thoracic kyphosis angle, lumbar lordosis angle, sagittal vertical axis, pelvic title and pelvic incidence were compared to evaluate the improvement in the sagittal vertical axis. The quality of life was evaluated with the Japanese Osteoporosis Quality of Life Questionnaire scores.
RESULTS AND CONCLUSION: (1) The Visual Analogue Scale and Oswestry Disability Index scores in the operation group were improved significantly compared the baseline. (2) The postoperative thoracic kyphosis angle, sagittal vertical axis, and pelvic title in the operation group were significantly improved compared with the baseline. (3) The postoperative posture, figure scores, and fear and physiological scores in the operation group were significantly improved compared with the baseline, but lower than those in the control group (P < 0.05). There were no significant differences in the pain and health scores between two groups postoperatively (P > 0.05). (4) These results indicate that spinal alignment and quality of life are significantly improved after corrective spinal surgery using multilevel posterior lumber interbody fusion and posterolateral fusion for patients with osteoporosis and thoracolumbar kyphosis. 

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程

Key words: Thoracic Vertebrae, Lumbar Vertebrae, Kyphosis, Spinal Fusion, Osteoporotic Fractures, Quality of Life, Tissue Engineering

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