Table of Content

08 November 2017, Volume 21 Issue 31 Previous Issue    Next Issue

For Selected:

Download Citations EndNote Reference Manager ProCite BibTeX RefWorks

Toggle Thumbnails

Select

Total hip arthroplasty with double mobility acetabular prosthesis: a 1-year follow up Lin Zuo-hua, Li Zhuo-wen, Li Can-hui, Chen Xiao-feng 2017, 21 (31):  4921-4926.  doi: 10.3969/j.issn.2095-4344.2017.31.001 Abstract ( 576 )   PDF (1253KB) ( 189 )   Save BACKGROUND: To solve the dislocation following hip arthroplasty, a double mobility acetabular prosthesis has been developed, and its effect still needs to be confirmed through follow-up observation. OBJECTIVE: To explore the early clinical effectiveness of total hip replacement with double mobility acetabular prosthesis. METHODS: Thirty patients admitted from January 2013 to November 2015, were given total hip replacement with double mobility acetabular prosthesis, and were then followed up for 1 year. The hip function and loosening were evaluated by Harris hip scores, Beijing program scaling and imaging examination. RESULTS AND CONCLUSION: (1) All patients were followed up for 1 year. (2) The mean Harris hip score was significantly increased from preoperatively (39.7±3.87) to postoperatively (93.6±3.82), and the mean score of the Beijing program scaling was also significantly increased from (10.5±2.46) to (17.3±1.87) (both P < 0.05). (3) All patients suffered from moderate to severe pain before replacement, and 28 patients complained mild or no pain and 2 patients with moderate pain after operation. X-ray showed a stable hip. (4) To conclude, the total hip arthroplasty with double mobility acetabular prosthesis achieves satisfactory short-term treatment outcomes, but its long-term effect needs to be observed further. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Prevention of the perioperative deep venous thrombosis in hip arthroplasty   Liu Jian-wei, Jiang Wei-ping 2017, 21 (31):  4927-4932.  doi: 10.3969/j.issn.2095-4344.2017.31.002 Abstract ( 444 )   PDF (1112KB) ( 195 )   Save BACKGROUND: A meta-analysis of the clinical effectiveness of physical therapy combined with drugs versus single physical therapy or drugs for preventing deep venous thrombosis (DVT) has shown that combined therapy can effectively reduce the incidence of DVT. OBJECTIVE: To explore the effective measures of the prevention of perioperative DVT in hip arthroplasty. METHODS: This is a prospective study, 350 patients undergoing hip replacement were randomly divided into two groups, followed by given the treatment of intermittent pneumatic compression combined with standard dose of low-molecular-weight heparin (combination group), or only low-molecular-weight heparin (control group). The perioperative incidence of DVT was observed. RESULTS AND CONCLUSION: (1) The incidence of DVT in the combination group was significantly lower than that in the control group (11% vs. 33.1%, P < 0.01). (2) No symptomatic pulmonary embolism was found in both groups. (3) To conclude, the anticoagulant prevention of DVT using the combination of intermittent pneumatic compression and standard dose of low-molecular-weight heparin is more effective than the use of low-molecular-weight heparin alone. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Total hip arthrolasty plus acetabular structural bone grafting for acetabular dysplasia combined with osteoarthritis Tang Xu 2017, 21 (31):  4933-4938.  doi: 10.3969/j.issn.2095-4344.2017.31.003 Abstract ( 342 )   PDF (1266KB) ( 188 )   Save BACKGROUND: Acetabular dysplasia is commonly seen in hip diseases, which can lead to biomechanical imbalance of the hip joint and accelerate the hip worn, further inducing hip osteoarthritis. At present, total hip arthroplasty is the preferred. OBJECTIVE: To investigate the clinical efficacy of total hip arthrolasty plus acetabular structural bone grafting in the treatment of acetabular dysplasia combined with osteoarthritis. METHODS: Fifty cases of acetabular dysplasia combined with osteoarthritis were enrolled, including 11 cases of Crowe I, 16 Crowe II, 19 Crowe III and 4 Crowe IV, and all were treated with total hip arthrolasty plus acetabular structural bone grafting. The pain, functional recovery, Harris hip score, and quality of life were recorded at baseline and 6 months after treatment. RESULTS AND CONCLUSION: After treatment, (1) the Harris hip scores in the patients with Crowe I, II, III, and IV acetabular dysplasia were significantly increased (P < 0.05); (2) the pain and walking were significantly improved in all patients (P < 0.05); (3) the patients’ physiological function, physiological function, body pain, health, energy, social function, emotional function and mental health were significantly improved (P < 0.05). (4) These results elaborate that total hip arthrolasty plus acetabular structural bone grafting to treat acetabular dysplasia combined with osteoarthritis, can obtain appropriate acetabular cup placement, excellent prosthesis supporting, restore limb length and increase acetabular bone mass. Therefore, it significantly improves patients’ pain and hip function, thereby improving patients’ quality of life and achieving satisfactory treatment outcomes.    中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Effects of combination therapy on the movement function of lower extremity after total knee arthroplasty in the elderly   Chen Hui, Du Shan-shan, Fan Li-juan, Jiang Jie, Liang Xiao-yan, Zhen Ping, Li Xu-sheng, Liu Jun 2017, 21 (31):  4939-4944.  doi: 10.3969/j.issn.2095-4344.2017.31.004 Abstract ( 376 )   PDF (1126KB) ( 203 )   Save BACKGROUND: Electromyographic biofeedback therapy has been reported to contribute to the functional recovery of the lower limb after arthroplasty. OBJECTIVE: To compare the effect of different rehabilitation therapies on the movement function of lower limb in elderly patients after total knee replacement. METHODS: Totally153 patients undergoing total knee replacement were randomly divided into conventional, electromyographic biofeedback and combination groups (n=51 per group), and then subjected to the conventional rehabilitation training, electromyographic biofeedback at the quadriceps femoris, and conventional rehabilitation training, electromyographic biofeedback plus body weight supported treadmill training, respectively. At 8 weeks after treatment, the movement function of lower limbs, activities of daily living and balance abilities, range of flexion-extension of the knee joint, walking ability, Hospital for Special Surgery of the lower limbs, as well as the Lower Extremity Functional Scale scores were evaluated. Besides, the Visual Analogue Scale scores, surface electromyogram of the quadriceps femoris at rest and in activity, co-contraction ratio of antagonistic muscle when ankle dorsiflexion, Fugl-Meyer assessment, modified Barthel index, Berg Balance Scale, and Holden walking function classification were detected. RESULTS AND CONCLUSION: (1) The Visual Analogue Scale scores after treatment in the combination group were significantly lower than those before treatment, in the conventional and electromyographic biofeedback groups (P < 0.01). (2) The Hospital for Special Surgery and Lower Extremity Functional Scale scores in the combination group were significantly higher than those in the conventional and electromyographic biofeedback groups (P < 0.05). (3) The surface electromyogram values, co-contraction ratio of antagonistic muscle, Fugl-Meyer assessment, modified Barthel index, range of flexion-extension of the knee joint, maximum step length and velocity as well as Holden walking function in the combination group were significantly superior to those in the conventional and electromyographic biofeedback groups (P < 0.05). (4) These results indicate that combination therapy is able to significantly improve the movement function and muscle strength of the lower limb, and enhance the postoperative rehabilitation for the elderly after total knee arthroplasty. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Effects of two analgesia methods on the stress response and hemodynamics during total knee arthroplasty Li Yuan, Xie Hai, Zhou Qi, Zhang Jiao 2017, 21 (31):  4945-4950.  doi: 10.3969/j.issn.2095-4344.2017.31.005 Abstract ( 279 )   PDF (1098KB) ( 162 )   Save BACKGROUND: Pain relief in patients with total knee arthroplasty has always been an important problem, and searching for a safe and effective analgesic method is an issue of concern. OBJECTIVE: To compare the effects of patient controlled nerve femoral analgesia and patient controlled epidural analgesia on the perioperative stress response and hemodynamics in patients with total knee arthroplasty. METHODS: Sixty patients undergoing unilateral total knee arthroplasty admitted in the First Affiliated Hospital of Hainan Medical University from August 2012 to January 2016 were selected and equally divided into observation and control groups according to the order of admission. The total knee arthroplasty was completed by the senior doctors using operation criteria. The patient controlled epidural analgesia analgesia was used in the control group, while the observation group received the patient controlled nerve femoral analgesia analgesia. The prognosis, perioperative stress response and hemodynamic changes were observed. RESULTS AND CONCLUSION: (1) The Visual Analogue Scale scores at postoperative 4, 24 and 48 hours in the observation group were significantly lower than those in the control group (P < 0.05). (2) The serum level of 5-hydroxytryptamine at postoperative 24 and 48 hours in the observation group was significantly lower than that in the control group (P < 0.05). (3) The American Knee Society Knee Score scores at baseline showed no significant difference between two groups, and then appeared to be on a significant rise postoperatively (P < 0.05), while the scores at postoperative 1 and 3 months in the observation group were significantly higher than those in the control group (P < 0.05). (4) The incidence of respiratory depression, urinary retention, atelectasis, skin itching, nausea and vomiting at postoperative 3 months in the observation group was significantly less than that in the control group (P < 0.05). (5) These results manifest that compared with the patient controlled epidural analgesia, the patient controlled nerve femoral analgesia in total knee arthroplasty can alleviate the stress response to pain and reduce the expression of 5-hydroxytryptamine and the incidence of complications, further promoting the recovery of joint function. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Three-dimensional printing-assisted atlantoaxial pedicle screw placement for type II C odontoid fracture   Zhang Shu-fang, Chen Rong-chun, Guo Chao-yang, Ye Shu-xi 2017, 21 (31):  4951-4956.  doi: 10.3969/j.issn.2095-4344.2017.31.006 Abstract ( 376 )   PDF (1026KB) ( 162 )   Save BACKGROUND: Three-dimensional (3D) printing has been widely applied in pelvic fracture and joint surgeries, but its feasibility in atlantoaxial pedicle screw placement needs to be studied further.  OBJECTIVE: To explore the feasibility and accuracy of 3D printing-assisted atlantoaxial pedicle screw placement in the treatment of type II C odontoid fracture. METHODS: Clinical data of 20 patients with type II C odontoid fracture admitted in the Ganzhou Hospital Affiliated to Nanchang University from June 2014 to December 2015 were analyzed retrospectively. The patients were randomized into two groups, and then received 3D printing-assisted atlantoaxial pedicle screw placement (experimental group), or conventional atlantoaxial pedicle screw placemen (control group). The placement was observed through X-ray and CT scanning. All patients were followed up for 12 months, and the clinical efficacy was assessed by Visual Analogue Scale and cervical Japanese Orthopaedic Association scores. RESULTS AND CONCLUSION: (1) The operation time, blood loss and radiation exposure time in the experimental group were significantly less than in the control group (P < 0.05). (2) The accuracy of placement in the experimental group was significantly higher than that in the control group (P < 0.05). No spinal cord, vertebral artery or nerve injuries occurred in the two groups. (3) The postoperative clinical efficacy was assessed by Visual Analogue Scale and cervical Japanese Orthopaedic Association scores in the two groups were significantly improved (P < 0.05). (4) These findings manifest that 3D printing-assisted trans-atlantoaxial pediele screw placement is a safe and effective method for type II C odontoid fracture. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Single segment fixation with atlantoaxial pedicle screws in the treatment of Jefferson fracture combined with unstable odontoid fracture Qu Wei, Yan Liang, Song Zong-rang, Liu Ji-jun, Wu Qi-ning, Hao Ding-jun 2017, 21 (31):  4957-4962.  doi: 10.3969/j.issn.2095-4344.2017.31.007 Abstract ( 381 )   PDF (1747KB) ( 195 )   Save BACKGROUND: Jefferson fracture associated with unstable odontoid fracture is rare, and little reported. Occipito-cervical fusion is the commonly used treatment method, but it causes a severe loss of the motion of cervical vertebrae, which affects the patients’ quality of life, so the curative effect is poor. OBJECTIVE: To evaluate the feasibility and therapeutic efficacy of atlantoaxial transpedicular screw fixation for Jefferson fracture associated with unstable odontoid fracture, so as to avoid occipito-cervical fusion and preserve the motion of the atlanto-occipital joint. METHODS: Fifteen patients with Jefferson fracture associated with unstable odontoid fracture from March 2010 to August 2015, were treated with atlantoaxial transpedicular screw fixation. There were 13 cases of Anderson type II and 2 cases of Anderson shallow type lll odontoid fracture, as well as 5 cases combined with transverse atlantal ligament rupture. All patients underwent skull traction after admission, as well as three-dimensional CT was applied preoperatively to determine the atlas pedicle screw trajectory and chose suitable screws. Atlantoaxial transpedicular screw was placed and atlantoaxial joint was reduced under general anesthesia. Bone graft fusion of atlantoaxial joint was applied only for the transverse atlantal ligament. The pain and neurologic function were evaluated by the Visual Analog Scale and the American Spinal Injury Association Impairment Scale before and after operation. The range of motion of the atlanto-occipital joint was observed during follow-up. RESULTS AND CONCLUSION: (1) The mean operation time was (150±41) minutes (120-270 minutes). The mean blood loss was (246±95) mL (160-500 mL). (2) Atlantoaxial transpedicular screws were successfully placed in all patients. No spinal and nerve root injury, or vertebral artery injury occurred intraoperatively. The atlantoaxial achieved good reduction. (3) The follow-up time was 12-36 months. There were nine cases of incomplete spinal cord injury, and 7 cases of obviously improved neurologic function. The visual analog scale scores were significantly improved at 1 year postoperatively, from preoperative (8.15±0.62) to postoperative (1.2±1.4) (P < 0.05). (4) All fractures and bone grafts were healed without loosening or rupture of the screws. The range of motion of the atlanto-occipital joint was (14.6±2.8)° postoperatively. (5) To conclude, atlantoaxial transpedicular screw fixation is effective for Jefferson fracture combined with unstable odontoid fracture, which not only exhibits a high rate of bone healing and stable fixation, but also avoids the occipital-cervical fusion and preserves occipito-atlantal motion.  中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Comparison study of the effect of fusion and non-fusion fixation on the movement of injured lumbar spine Song Hong-fang, Zhang Wen, Zhang Qiang, Liu Zhi-cheng 2017, 21 (31):  4963-4968.  doi: 10.3969/j.issn.2095-4344.2017.31.008 Abstract ( 301 )   PDF (1376KB) ( 153 )   Save BACKGROUND: Degenerative change in lumbar spine is the natural physiological and pathological process with age increasing, which seriously affects the patients’ quality of life. Conventional surgical treatments may bring about some complications. Interspinous stabilization Coflex demonstrates good clinical outcomes, while there is lack of experimental evidence. OBJECTIVE: To investigate the effect of fixation methods on the movement of lumbar vertebrae, and to provide reference for clinical operation from the aspect of biomechanics. METHODS: Five fresh specimens of pig cadaveric lumbar spine were selected and divided into five groups: blank control group (group A), injury group (group B), L3-L4 Coflex fixed (group C), L3-L4 Coflex fixed plus decompression (group D), and L3-L4 intervertebral fusion fixed (group E). The biomechanical performance of the five lumbar specimens was tested in six loading directions of flexion/extension, left/right lateral bending, and left/right axial rotation driven by a robot system. The motion range of the operation segments (L3-L4) and the whole lumbar spine was observed by a multi-directional torque sensor combined with a three-dimensional motion capture system. Finally, the influence of lumber fixation methods on the spinal movement was explored. RESULTS AND CONCLUSION: (1) For the range of three-dimensional angle at the operation segments (L3-L4), it was found that groups C and D were similar to group A, and groups B and E were quite different from group A. (2) Group E could restore the motion range of the injured segments, but the motion angle was much smaller than that in the groups C and D. (3) These results indicate that the motion angle of the injured spine treated with Coflex can restore to the normal state, with long-term stability. For unstable lumbar spine, interspinous Coflex is better than transforaminal lumbar interbody fusion, which can induce similar biomechanical properties to normal lumbar spine after operation.   中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Preventing the screw from loosening and pulling out, secondary lumbar spondylolisthesis: how to select a better therapeutic scheme for osteoporotic lumbar spondylolisthesis? Chen Xiao, Shao Gao-hai, Xu Hai-tao 2017, 21 (31):  4969-4974.  doi: 10.3969/j.issn.2095-4344.2017.31.009 Abstract ( 475 )   PDF (1109KB) ( 149 )   Save BACKGROUND: Expansive pedicle screws have been found to have strong resistance to rotation, prevent screw loosening and pulling out, and maintain the stability and physiological curvature of lumbar vertebrae, so it provides a secure and stable environment for long-tem intervertebral fusion. OBJECTIVE: To investigate the clinical efficacy of the expandable versus conventional pedicle screws in the treatment of osteoporotic lumbar spondylolisthesis. METHODS: A total of 67 cases of osteoporotic lumbar spondylolisthesis were randomized into three groups, and then treated with conservative treatment (n=12), expansive pedicle screws (n=20), and common pedicle screws (n=35), respectively. The Japanese Orthopaedic Association and Visual Analogue Scale scores as well as radiological data were obtained immediately and 1 week after admission, 6 and 12 months after discharge. The stability of the screw and spinal fusion were evaluated, and the spondylolisthesis was assessed according to Meyerding system. RESULTS AND CONCLUSION: (1) The improvement rate of Japanese Orthopaedic Association scores at the last follow-up showed no significant difference between expansive and common groups (P=1.00), and the improvement rate in the expansive and common groups was significantly higher than that in the conservative group (P < 0.05). (2) The Visual Analogue Scale scores in the expansive and common groups were significantly decreased, and the scores did not differ significantly between two groups (P > 0.05); the scores in the conservative group changed irregularly. (3) The reduction rate of spondylolisthesis in the expansive group was significantly higher than that in the common group (P < 0.01). (4) The spinal fusion score at 24 months postoperatively in the expansive group was significantly higher than that in the common group (P=0.035). (5) For osteoporotic patients with lumbar spondylolisthesis, the expansive pedicle screws are much better than the common pedicle screws in the spondylolisthesis reduction, fusion rate of bone graft, screw stability; therefore, it is a safer and more effective method. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Modification and validation of Lenke3 type adult idiopathic scoliosis finite element model Xin Da-qi, Hu Zhen-ming, Han Di, Yang Xue-jun, Xiao Yu-long, Xing Wen-hua, Zhao Yan, Fu Yu, Zhu Yong 2017, 21 (31):  4975-4982.  doi: 10.3969/j.issn.2095-4344.2017.31.010 Abstract ( 346 )   PDF (2028KB) ( 182 )   Save BACKGROUND: A Lenke3 type adult idiopathic scoliosis finite element model was established successfully using Mimics software. However, whether the model fits the actual conditions of individualized patients still requires a further revision and validation. OBJECTIVE: To modify and validate the Lenke3 type adult idiopathic scoliosis finite element model by finite element analysis software. METHODS: Based on the characteristics of Lenke3 adult idiopathic scoliosis model, the three-factor and three-level orthogonal experiment was used to optimize the finite element model, making it more close to the actual one. The vertebrae at T1-T4, T5-T8 and L6-S1 levels (sacral lumbarization) were loaded to simulate left and right lateral flexion, as well as extension and flexion, and the range of motion when left and right rotation were compared with Busscher and Yamamoto experiments in vitro. RESULTS AND CONCLUSION: (1) According to the orthogonal experiment, the mean difference and range of each factor and each level were calculated, and finally A1B2C3 combination was the optimal one that can make the model largely consistent with the real situation. The difference in Cobb angles between the clinical lateral flexion test and the parameter pre-modified model simulation was 54.44°, which was decreased to 2.11° after modification. Moreover, the maximum difference in each scoliosis Cobb angle of the modified model was 4.29°. (2) The simulation results of the modified model when compared with the X-ray images when left and right lateral flexion, the two data obeyed normal distribution, so the paired t test was used: left lateral flexion, P =0.082 (P > 0.05); right lateral flexion, P=0.421 (P > 0.05); supine position, P=0.160 (P > 0.05). (3) The range of motion at T1-T4 segments was as followings: left flexion, 3.25°; right flexion, 3.32°; anteflexion 2.52°; extension, 2.89°; left rotation, 3.73°; right rotation 3.76°; the range of motion at T5-T8 segments: left flexion, 1.39°; right flexion, 1.43°; anteflexion 1.35°; extension, 1.34°; left rotation 2.09°; right rotation 2.11°; the range of motion at L6/S1: left flexion: 5.17°; right flexion: 5.19°; anteflexion: 8.92°; extension: 7.35°; left rotation: 1.41°; right rotation: 1.42°. The results were almost consistent with Busscher and Yamamoto experimental results. (4) To conclude, the model is in good agreement with the patient’s actual properties after modification. The modified model has good reliability and validity, and provides valid data platform for simulating clinical operation in the future.  中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Biomechanics of osteonecrosis of femoral head after tantalum rod implantation: a three-dimensional finite element analysis   Ou Zhi-xue, Ling Guan-han, Yao Lan, Lin Heng-feng 2017, 21 (31):  4983-4988.  doi: 10.3969/j.issn.2095-4344.2017.31.011 Abstract ( 304 )   PDF (1088KB) ( 151 )   Save BACKGROUND: The femoral anterolateral column plays a key role in hip preservation surgery, and the China-Japan Friendship Hospital (CJFH) type stresses the anterolateral column, but there is little information available in three-dimensional (3D) finite element analysis of the L-type tantalum rod implantation. OBJECTIVE: To establish a 3D finite element model of L-type tantalum rod implantation into the normal, necrotic and L-type necrotic areas, followed by a finite element analysis, and to explore the importance of the integrity of the anterolateral column for hip preservation surgery, thus providing biomechanical evidence for the treatment of CJFH type. METHODS: Based on the prepared 3D models of CJFH L1, L2 and L3 osteonecrosis of the femoral head (ONFH) and normal hip, the 3D finite element model of tantalum rod implantation of femoral head necrosis was established, and finite element analysis was conducted. The stress distribution and the maximum Mises stress value of cortical shell of normal femoral head, necrotic femoral head and tantalum rod implanted ONFH were observed and compared. RESULTS AND CONCLUSION: (1) The maximum Mises of the weight-bearing area of cortical bone shell of L-type ONGH was higher than that of normal femoral, L1. L2 and L3 increased by 21.76%, 31.02%, and 42.79%, respectively. (2) The maximum Mises of weight-bearing area of cortical bone shell was decreased after tantalum rod implantation, L1 L2 and L3 decreased by 13.38%, 8.81%, and 11.45%, respectively. (3) In necrotic femoral head, the decreased bearing stress, leads to stress concentration on the femoral head bone shell, so the maximum is higher than that of the normal condition. The higher classification is, the greater the stress concentration of the cortical bone shell is. Tantalum rod implantation share certain stress. (4) Tantalum rod implantation corrects some stresses of the bone shell of ONFH, and can prevent collapse and exert the biomechanical effect of supporting subchondral bone. Furthermore, the integrity of the lateral column of the necrotic femoral head affects the efficacy of hip preservation, and more lateral column preserved always accompanied with better hip preservation. The higher CJFH classification exhibits a higher risk of collapse, and poorer hip preservation. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Short-term efficacy of the proximal femoral nail antirotation system versus intertrochanteric antegrade nail system in the treatment of femoral intertrochanteric fracture    Liang Ning, Jiang Jun, Qiu Hai-bin, Daniel Porter, Wang Zhan-chang 2017, 21 (31):  4989-4994.  doi: 10.3969/j.issn.2095-4344.2017.31.012 Abstract ( 320 )   PDF (1117KB) ( 185 )   Save BACKGROUND: Femoral intertrochanteric fracture is a common fracture type in elderly patients, and which kind of internal fixation system is better remains controversial. OBJECTIVE: To investigate the short-term efficacy of proximal femoral nail antirotation (PFNA) system versus intertrochanteric antegrade nail (InterTan) system in the treatment of femoral intertrochanteric fracture. METHODS: Forty-five patients with femoral intertrochanteric fracture were divided into PFNA (n=19) and InterTan (n=26) groups. The operation time, intraoperative blood loss hospitalization time, incidence of complications and Harris hip scores at postoperative 3 months were compared between two groups. RESULTS AND CONCLUSION: (1) Patients with PFNAs enjoyed a significantly shorter operation time at (125.8±21.5) minutes compared those with InterTans who needed (156.2±54.5) minutes (P < 0.05). (2) The intraoperative blood loss in the PFNA and InterTan groups was (226.3±107.2) mL and (300.0±150.3) mL, respectively, but the difference was not significant (P > 0.05). (3) No significant difference was identified in the hospitalization time, incidence of complications and Harris hip scores at postoperative 3 months between two groups (P > 0.05). (5) Our findings indicate that except for short operation time in PFNA system, there are no significant differences in the intraoperative blood loss, hospitalization time, incidence of complications and Harris hip scores at postoperative 3 months between two internal fixation systems, and both possess good safety and efficacy in postoperative short period. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Effects of percutaneous compression plate versus proximal femoral nail anti-rotation internal fixation on the postoperative functional recovery and femoral head rotation and nail slippage in elderly patients with stable intertrochanteric fracture   Zhang Lei, Zhou Zheng-ming, Gu Jia-ye, Yin Xiao-jun, Lu Dong 2017, 21 (31):  4995-5000.  doi: 10.3969/j.issn.2095-4344.2017.31.013 Abstract ( 398 )   PDF (1170KB) ( 156 )   Save BACKGROUND: Senile unstable intertrochanteric fractures are usually treated with intramedullary nail fixation, but for stable intertrochanteric fractures, extramedullary fixation and intramedullary nail both can obtain satisfactory curative efficacy. Therefore, surgical options are still a controversy. OBJECTIVE: To investigate the effect of percutaneous compression plate (PCCP) versus proximal femoral nail anti-rotation (PFNA) on the postoperative functional recovery of the elderly with stable intertrochanteric fractures and to observe the rotational stability and nail slipping. METHODS: Totally 86 elderly patients with stable intertrochanteric fracture were randomly divided into two groups, and then underwent PCCP or PFNA. The operation time, intraoperative blood loss, postoperative hemoglobin level, the time of weigh bearing, and fracture healing time were recorded; Harris hip scores at postoperative 4 weeks were detected to assess the functional recovery; the rotation rate of femoral head and incidence of nail slipping at 4 weeks postoperatively, as well as the complications within 6 months postoperatively were analyzed statistically. RESULTS AND CONCLUSION: (1) The intraoperative and postoperative declined levels of hemoglobin in the PFNA group were significantly higher than those in the PCCP group (P < 0.05). (2) There was no significant difference for in the Harris hip scores between two groups at postoperative 4 weeks (P > 0.05). The weight bearing time and fracture healing time in the PFNA group were significantly shorter than those in the PCCP group (P < 0.05). (3) The rotation rate of femoral head and nail slipping in the PFNA group were significantly lower than those in the PCCP group (P < 0.05). (4) The incidence of complications within 6 months postoperatively did not differ significantly between two groups (P > 0.05). (5) These results suggest that there is no significant difference in the postoperative function recovery and complications between PCCP and PFNA in the treatment of senile femoral intertrochanteric fracture fixation. However, PFNA possesses advantages in the rotation rate of femoral head and nail slipping.  中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Minimally invasive closed reduction and internal fixation with fully threaded headless cannulated compression screws for repair of distal radius fracture: study protocol for a randomized controlled trial    Yang Li-feng, Zhang Yang, Wang Nan, Ma Ji, Li Zhi 2017, 21 (31):  5001-5506.  doi: 10.3969/j.issn.2095-4344.2017.31.014 Abstract ( 299 )   PDF (854KB) ( 175 )   Save BACKGROUND: Conventional open reduction internal fixation and external fixation are not ideal treatment options for distal radius fracture. Minimally invasive surgery for distal radius fracture results in less trauma than other techniques; fully threaded headless cannulated compression screws can increase the stability of fracture fragments and contribute to functional recovery after wrist fracture. Our previous studies have found that minimally invasive closed reduction and internal fixation of distal radius fracture with fully threaded headless cannulated compression screws obtains satisfactory curative efficacy, especially for fracture involving the wrist joint, but no more than two fracture fragments. OBJECTIVE: We hypothesized that minimally invasive closed reduction and internal fixation with fully threaded headless cannulated compression screws provides better stability than conventional methods, and can effectively promote the early recovery of wrist function. METHODS: In this prospective, randomized, controlled trial, we will recruit 60 outpatients with distal radius fracture from the Department of Orthopedic Surgery, Central Hospital Affiliated to Shenyang Medical College, China. Patients will be assigned to one of two treatment groups: C-arm fluoroscopy-assisted minimally invasive closed reduction and internal fixation with fully threaded headless cannulated compression screws (experimental group) or open reduction (palmar and dorsal incisions) and internal fixation with titanium plate (control group). Internal fixation will be maintained for 24 weeks in both groups. Our primary outcome measure will be X-ray and CT examinations 24 weeks after surgery. Secondary measures include patient-rated wrist evaluation scores, used to evaluate wrist joint function; fracture healing time; and Visual Analogue Scale score, used to evaluate the severity of the patient’s pain. This trial has been registered at ClinicalTrials.gov (identifier: NCT02784678). The study protocol has been approved by the Ethics Committee of Central Hospital Affiliated to Shenyang Medical College, China. The trial protocol will be performed in accordance with the guidelines of the Declaration of Helsinki, formulated by the World Medical Association (General Assembly of the World Medical Association, 2014). DISCUSSION: With this study, we hope to confirm that minimally invasive closed reduction and internal fixation with fully threaded headless cannulated compression screws for distal radius fracture repair has advantages over conventional open reduction internal fixation with titanium plates, providing superior fragment stability and allowing for early rehabilitation exercise of the wrist joint, which improves recovery of function. We hope to show that minimally invasive closed reduction and internal fixation with fully threaded headless cannulated compression screws is suitable surgical method for repair of distal radius fracture. Figures and Tables | References | Related Articles | Metrics

Select

Postoperative gait analysis of acute posterolateral rotatory dislocation of knee joint and its guiding significance Huang Hua-qiang, Yun Zhu, Jiang Hai, Fu Wei-li, Li Jian, Tang Xin 2017, 21 (31):  5007-5013.  doi: 10.3969/j.issn.2095-4344.2017.31.015 Abstract ( 402 )   PDF (1270KB) ( 164 )   Save BACKGROUND: The evaluation for posterolateral rotatory dislocation of knee joint often relys on traditional imaging techniques to obtain static anatomical information; meanwhile, the knee function was assessed by Lysholm and the International Knee Documentation Committee scores. However, none can quantitatively evaluate the kinematic characteristics, let alone providing guidance for postoperative rehabilitation. OBJECTIVE: To analyze the gait characters of the patients with acute posterolateral rotatory dislocation of knee joint and to dynamically evaluate the postoperative kinematic parameters and displacement indicators, thereby providing guidance for rehabilitation. METHODS: Twelve patients with acute knee posterolateral rotatory dislocation were admitted in the West China Hospital, Sichuan University between January 2011 and December 2014, and all patients underwent one-stage reconstruction or repair of ligaments under arthroscopy, followed by routine rehabilitation training. Opti-Knee® analysis system was used to collect 6 degrees of freedom (movement angle and displacement) of the ipsilateral (injury group) and contralateral knee joints (normal group), the change levels were calculated, and were then compared between two groups. RESULTS AND CONCLUSION: (1) There was no significant difference in the maximum varus/valgus angles and maximum intersion/extorsion angles (P > 0.05). While, the minimum flexion angle, maximum flexion angle, as well as the change level of flexion/extension angles, varus/valgus angles and maximum intersion/extorsion angles in the injury group were significantly higher than those in the normal group (P < 0.05). (2) There was no significant difference in the maximum forward, inward and outward displacement as well as the change levels of inward/outward displacement between two groups (P > 0.05). The maximum backward, and downward displacement as well as the change levels of forward/backward displacement in the injury group were significantly higher than those in the normal group; while the maximum upward displacement and the change levels of upward/downward displacement in the injury group were significantly lower than those in the normal group (P < 0.05). (3) These results suggest that the arthroscopy-assisted one-stage treatment of the acute posterolateral rotatory dislocation of the knee joint can remarkably restore the gait. Opti-Knee® analysis system can provide objective information of motion parameters, and the change in the degree of freedom provides guidance for clinical rehabilitation. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Stress rate and creep behaviors of cancellous bone under uniaxial compression Wei Chao-lei, Gao Li-lan, Zhang Chun-qiu, Liu Dong-dong, Jiang Wang-biao 2017, 21 (31):  5014-5018.  doi: 10.3969/j.issn.2095-4344.2017.31.016 Abstract ( 366 )   PDF (941KB) ( 169 )   Save BACKGROUND: Cancellous bone, as an important part of bone, is a kind of porous, inhomogeneous, anisotropic and viscoelastic structure, which plays a critical role in load transmission and energy absorption. Therefore, research on its mechanical properties is of great significance. OBJECTIVE: To investigate the compressive properties of cancellous bone at different stress rates and its creep behaviors at different stress levels. METHODS: The fresh cancellous bone from pig femur was used as the material, and subjected to different stress until the compressive strain of sample was up to 5%. The constant compressive stress levels were loaded on the surface of cancellous bone for 7 200 s to observe its creep behaviors. RESULTS AND CONCLUSION: (1) In the uniaxial compression test, the stress values and Young’s modulus increased with the stress rate increasing under the same strain value. (2) The stress-strain curves of cancellous bone were different at different loading rates, indicating that the mechanical properties of cancellous bone depend on the loading rate. (3) In the creep test, the creep strain increased with the increase of stress level, but the creep compliance decreased with the increase of stress level. (4) These results suggest that the stress rate and stress level have significant influence on compressive properties of cancellous bone, which provide reference for avoiding cancellous bone injury. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Finite element analysis of the biomechanical characteristics of ankylosing kyphosis osteotomy using the vertebral column decancellation and the vertebral column resection   Duan Yan-ji, Ma Jun-yi, Li Hui, Li Li, Ma Yuan 2017, 21 (31):  5019-5024.  doi: 10.3969/j.issn.2095-4344.2017.31.017 Abstract ( 299 )   PDF (1289KB) ( 175 )   Save BACKGROUND: Patients with severe ankylosing kyphosis are often treated with orthopedic osteotomy, but with high surgical risk, treatment schemes are individualized, and the biological morphology and mechanical properties of the deformed spine are complex. Meanwhile, the finite element model is more adaptable for biomechanical analysis of the spinal deformity. However, its application in the treatment of ankylosing kyphosis in China was little reported. OBJECTIVE: To establish an ankylosing kyphosis finite element model so as to investigate the relationship between different osteotomy methods and the deformation and stress distribution of the spine. METHODS: A three-dimensional finite element model of ankylosing kyphosis was established, and then imported into ANASYS software, to simulate vertebral column decancellation and vertebral column resection at T12 and L1 levels, respectively. The vertebrae and screw were loaded with the same load, and deformation and stress nephograms were obtained. RESULTS AND CONCLUSION: (1) The deformation of the osteotomy at T12 level was significantly larger than that at L1 level. (2) The stress distribution of the decancellation osteotomy concentrated on the pedicle screw and titanium bar; the stress concentration of vertebral column resection was the intervertebral cage. (3) Individualized surgical treatment of ankylosing kyphosis may influence the selection of the osteotomy segment and osteotomy operation. The osteotomy segment may affect the stability of the spine, and stress distribution of internal fixation is likely related to the method of internal fixation. (4) This conclusion may provide theoretical reference for the biomechanical study of analysing ankylosing kyphosis. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Correlation of the pathologic morphology on MRI with International Hip Dysplasia Institute classification in developmental dysplasia of the hip   Yu Jing-hang, Liu Shuang, Li Lian-yong, Wang En-bo, Zhang Li-jun 2017, 21 (31):  5025-5030.  doi: 10.3969/j.issn.2095-4344.2017.31.018 Abstract ( 542 )   PDF (993KB) ( 217 )   Save BACKGROUND: Tönnis classification is commonly used to quantify the severity of developmental dysplasia of the hip (DDH), which relies on the presence of the epiphyseal ossification centre. Thereafter, a new classification system (IHDI method) has been developed by the International Hip Dysplasia Institute (IHDI). However, the pathologic morphology has not been defined based on the IHDI grade. OBJECTIVE: To analyze the correlation of the pathologic changes of the hip on MRI with IHDI classification. METHODS: Image data of 65 infants (89 hips) with DDH were analyzed retrospectively, with an average age of 20.4 months. The radiographic severity was graded by IHDI system, and the correlation between IHDI classification and pathological changes of the hip was analyzed, by observing the morphology and position of the limbus, and the cartilaginous acetabular index. RESULTS AND CONCLUSION: (1) A positive correlation was detected between severity of the IHDI grades and age at reduction (r=0.456, P < 0.001). (2) Unexpectedly, the cartilaginous femoral epiphysis still remained contacting with the acetabulum in a part of type III DDH. The cartilaginous acetabular index was significantly increased with IHDI grade increasing (P=0.028). (3) The limbus was everted in all of the type I hips; however, inverted or mixed shape accounted about 60% in the type II hips, 86% in the type III, and 97% in the type IV, respectively. (4) These results manifest that the DDH was severer, and the limbus trended to be more inverted with the increasing in IHDI grade. Moreover, understanding the correlation of the pathologic morphology with the IHDI classification is of great significance for planning an appropriate treatment scheme for DDH. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Magnetic resonance T1ρ versus T2 mapping for evaluating ischemic lumbar intervertebral disc degeneration in a rabbit model  Meng Zhong-meng, Pan Xi-min, Chen Ying-ming, Chen Li-qiang, Wu Zhi-qiang, Zhuang Wen-quan 2017, 21 (31):  5031-5035.  doi: 10.3969/j.issn.2095-4344.2017.31.019 Abstract ( 406 )   PDF (1173KB) ( 154 )   Save BACKGROUND: MRI T1ρ and T2 mapping have been applied to study lumbar intervertebral disc degeneration in human and rhesus monkey, showing that they can be used for evaluating the early degeneration, but their application in New Zealand rabbit lumbar intervertebral disc degeneration is never reported. OBJECTIVE: To compare the relaxation time values of T1ρ and T2 mapping at different time points in a New Zealand rabbit model of ischemic lumbar intervertebral disc degeneration, and to compare the sensitivity for degeneration. METHODS: Fifteen New Zealand rabbits were randomly divided into three groups, and one of intervertebral discs at L4-5, L5-6 and L6-7 was designed for ischemic lumbar intervertebral disc degenerative model and the other two discs for controls. All the rabbits underwent T1ρ and T2 mapping preoperatively, 1, 3 or 6 months postoperatively to analyze the changes in the relaxation time at different time points. RESULTS AND CONCLUSION: (1) In the modeling group, the T2 mapping relaxation time of nucleus pulposus was (118.53±20.51) ms and (85.42±11.65) ms at 3 and 6 months after modeling, respectively, which showed significant difference when compared with preoperatively (146.21±16.93) ms (P < 0.05); but the time showed no significant difference compared with 1 month after modeling (P > 0.05). (2)T1ρ relaxation time of nucleus pulposus was (64.75±14.63) ms at 6 months after modeling, which showed significant difference when compared with preoperatively (87.88±8.87) ms (P < 0.05); but the time showed no significant difference compared with 1 and 3 months after modeling (P > 0.05). (3) In the control group, there was no significant difference in the T1ρ or T2 mapping relaxation time of nucleus pulposus before operation with 1, 3 or 6 months after operation (P > 0.05). The Pfirrmann grade of lumbar intervertebral disc was changed to Pfirrmann grades II-III at 6 months after modeling. (4) These results suggest that MR T1ρ and T2 mapping both are quantitative tools for evaluating the progress of ischemic lumbar intervertebral disc degeneration in New Zealand rabbits, especially the T2 mapping MRI may be more sensitive to early degenerative changes. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Effects of MRI in the diagnosis and prognosis of cervical spinal cord injury without fracture or dislocation   Liu Xin-ge, Li Tao, Chen Fang-min, Han Dun-fu, Shi Ming 2017, 21 (31):  5036-5041.  doi: 10.3969/j.issn.2095-4344.2017.31.020 Abstract ( 279 )   PDF (1121KB) ( 157 )   Save BACKGROUND: In the elderly, the cervical vertebrae will appear with different degrees of spinal stenosis caused by various factors. Notably, the incidence of cervical spinal cord injury without fracture or dislocation is high, accounting for 3%-16% of cervical spinal cord injury. OBJECTIVE: To explore the efficacy of MRI in the diagnosis and prognosis of cervical spinal cord injury without fracture or dislocation, and to analyze the influencing factors for surgical effectiveness. METHODS: Fifty-one patients with cervical spinal cord injury without fracture or dislocation in Zibo Central Hospital from August 2014 to June 2016 were analyzed retrospectively. All the patients underwent anterior, posteror, or anterior-posterior fusion, respectively, and then the intraoperative ligament injury and MRI images were compared. The age, injury type, spinal cord injury type revealed on MRI, time from injury to hospital, signal length of spinal cord injury, American Spinal injury Association grade, degree of cervical stenosis, whether hormone used or not within 8 hours after injury, time from injury to surgery, and surgical approaches were analyzed based on univariate analysis and multivariate analysis by Logistic regression analysis. RESULTS AND CONCLUSION: (1) MRI showed more comprehensive damage of the spinal cord and intervertebral disc ligament complex than the intraoperative findings (χ2=5.966，P < 0.05), and the cervical spinal cord injury was related to the injury of the corresponding intervertebral disc ligament complex (χ2=1.53, P > 0.05). (2) Univariate analysis results showed that the spinal cord injury type revealed on MRI, signal length of spinal cord injury, American Spinal injury Association grade, degrees of cervical stenosis, whether hormone used or not within 8 hours after injury, and time from injury to surgery were related to the functional recovery of spinal cord (P < 0.01). (3) Multivariate analysis results indicated that the type revealed on MRI, signal length of spinal cord injury and degrees of cervical stenosis were significantly related to the functional recovery of spinal cord (P < 0.05). (4) These results suggest that MRI has a high tissue resolution, so it plays an important role in the diagnosis of cervical spinal cord injury without fracture or dislocation. Moreover, the degrees of spinal cord injury and spinal stenosis, as well as operation time are main factors for curative efficacy.  中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Application value of nerve root sedimentation sign in lumbar spinal stenosis revealed on MRI Chen Yan-chao, Yu Zuo-chong, Cao Rong, Yin Wang-ping 2017, 21 (31):  5042-5047.  doi: 10.3969/j.issn.2095-4344.2017.31.021 Abstract ( 466 )   PDF (948KB) ( 213 )   Save BACKGROUND: Clinical value of the nerve root sedimentation sign in patients with lumbar spinal stenosis (LSS) is still uncertain. OBJECTIVE: To investigate the positive rate and correlation of the nerve root sedimentation sign in patients with LSS. METHODS: Totally 281 patients complaining lumbago or low back pain underwent MRI examination in the Orthopedic Clinic or Ward of Jinshan Hospital of Fudan University, including 119 males and 162 females. The cross-sectional area and sagittal diameter of the spinal canal were measured, and the patients were then divided into two groups according to the presence and absence of LSS. Finally, the positive rate of nerve root sedimentation sign was compared. RESULTS AND CONCLUSION: (1) Grouping based on the presence and absence dural sac cross-sectional area stenosis: the positive rate of nerve root sedimentation sign in sever, non, and mild LSS patients was 91.4%, 39.6%, and 53.5%, respectively, and the difference was significant (P < 0.05), but the positive rate showed no significant difference between mild and moderate as well as moderate and severe LSS patients. (2) Grouping according to the presence and absence spinal canal sagittal diameter stenosis: there was a significant difference in the positive rate of nerve root sedimentation sign between non-LSS and LSS patients (44.3% vs. 76.1%, χ2=21.469, P=0.000). (3) Grouping based on the dural sac cross-sectional area combined with spinal canal sagittal diameter: the dural sac cross-sectional area < 120 mm2 or the spinal canal sagittal diameter < 10 mm indicating LSS, there was a significant difference in the positive rate of nerve root sedimentation sign between non-LSS and LSS patients (40.6% vs. 80.6%,χ2=30.539, P=0.000). (4) These results indicate that the diagnosis value of nerve root sedimentation sign in LSS is still under discussion. Although a positive sedimentation sign exclusively and reliably occurs in patients with severe LSS, it is also higher in patients without LSS. It may be inappropriate to take nerve root sedimentation sign as a diagnostic tool, but when combined with dural sac cross-sectional area and sagittal canal subsidence, it will be of great significance for the diagnosis of LSS. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Dermal hypoesthesia surrounding the incision after total knee arthroplasty: how to treat?   Han Yan-hong, Pan Jian-ke, Liu Jun, Yang Wei-yi, Cao Xue-wei, Guo Da 2017, 21 (31):  5048-5053.  doi: 10.3969/j.issn.2095-4344.2017.31.022 Abstract ( 336 )   PDF (1249KB) ( 170 )   Save BACKGROUND: Dermal hypoesthesia surrounding the incision usually occurs after total knee arthroplasty (TKA), which severely affects the patients’ life quality. But the relevant studies are still immature, and its prevention methods and prognosis remain controversial.  OBJECTIVE: To review the research and progress of dermal hypoesthesia following TKA. METHODS: A computer-based online research of CJFD, WanFang, VIP and Medline databases was performed for the literature addressing the dermal hypoesthesia surrounding the incision after TKA published from December 2001 to December 2016. The keywords were “total knee arthroplasty, incision, numbness, abnormal sensation” in English and Chinese, respectively. Finally, 36 eligible articles were selected for result analysis after excluding the repetitive ones. RESULTS AND CONCLUSION: (1) Dermal hypoesthesia surrounding the incision following TKA is commonly seen, but the related researches are few. Most of researches concentration on protecting against cutaneous nerve injury by modifying surgical approach, nerve conduit, neural nutrients and surgical repair, but all possess certain shortcomings, so there is a lack ideal prevention scheme. (2) The repairing methods for peripheral nerve injury, including biomolecular, cell and catheter therapies, have been applied in the repair of cutaneous nerve injury following TKA, but still on initial stage, and its effectiveness and safety need to be confirmed in depth. (3) Therefore, whether dermal hypoesthesia surrounding the incision following TKA needs treatment or not, and how to treat is an urgent problem for joint surgeon. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Total hip arthroplasty with collum femoris preserving prosthesis: differences from traditional prosthesis Huang He-tao, Pan Jian-ke, Xie Hui, Yang Wei-yi, Liang Hao-dong, Liu Jun 2017, 21 (31):  5054-5059.  doi: 10.3969/j.issn.2095-4344.2017.31.023 Abstract ( 313 )   PDF (1076KB) ( 184 )   Save BACKGROUND: Traditional total hip arthroplasty can easily lead to the postoperative complications such as prosthetic loosening and subsidence. The unique design concept of collum femoris preserving (CFP) prosthesis, effectively solves the above problems. OBJECTIVE: To summarize the research progress of CFP prosthesis in total hip arthroplasty. METHODS: A computer-based online retrieval in CNKI, CBM, VIP, WanFang, PubMed, Embase, The Cochrane Library, Web of Science databases from1990 to 2017 was performed with the keywords of “collum femoris preserving, CFP, total hip arthroplasty, TKA” in English and Chinese, respectively. The development history of CFP, design concept, surgical indications and contraindications, complications, surgical considerations as well as clinical effectiveness were analyzed and summarized. RESULTS AND CONCLUSION: A total of 41 articles were included. The stress distribution of CFU prosthesis is similar with the physical condition of proximal femur. The preserved normal eccentricity has good resistance to rotation, thus effectively avoiding prosthetic loosening and subsidence resulting from osteoporotic proximal femur, and still keeps more bone reserve for future revision surgery. Most of studies only prove that the CFP prosthesis has a certain curative efficacy, but the differences between traditional and CFP prosthesis remain unclear. A large number of high-quality evidence-based medicine and clinical researches are needed to support the clinical application of CFP prosthesis, thus providing data reference for orthopedic surgeons.   中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Transpedicular screw fixation for thoracolumbar fracture based on finite element analysis   Hao Shen-shen, Zhao Ru-yuan, Liu Zhi-bin, Wang Bo-wen, Cao Xin-hao, Xue Xiao-wei 2017, 21 (31):  5060-5065.  doi: 10.3969/j.issn.2095-4344.2017.31.024 Abstract ( 362 )   PDF (1210KB) ( 157 )   Save BACKGROUND: Thoracolumbar fracture is commonly seen in spinal injuries, which causes loss of stability of the spine, as well as spinal cord and nerve compression, even deformity and paralysis. The diagnosis and treatment of thoracolumbar fracture remain controversial. OBJECTIVE: To summarize the mechanism of thoracolumbar fracture based on finite element method, its classification and transpedicular screw fixation. METHODS: The first author retrieved CNKI and PubMed databases for the relevant literature published between January 2000 and December 2016. The keywords were “finite element method, thoracolumbar spine fracture, transpedicular screw fixation” in Chinese and English, respectively. RESULTS AND CONCLUSION: (1) The finite element analysis method can simulate the mechanism of thoracolumbar fracture and provides a reference for the studies on the occurrence, development and treatment of thoracolumbar fracture. (2) The classification of thoracolumbar fracture is beneficial for planning a rational treatment strategy and evaluating prognosis. (3) Compared with the traditional screw fixation, the transpedicular screw fixation holds advantages in biomechanical stability and postoperative correction effect. (4) There are various classifications for thoracolumbar fracture; differences in severity and cartilage injury are difficult to simulate completely. (5) The finite element analysis method shows certain application limitations due to long learning curve and modeling time as well as complicated calculations. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Association of lumbar facet tropism and orientation with lumbar disc herniation Zhou Qiang, Teng Dong-hui, Jiang Wen-xue 2017, 21 (31):  5066-5071.  doi: 10.3969/j.issn.2095-4344.2017.31.025 Abstract ( 371 )   PDF (964KB) ( 186 )   Save BACKGROUND: Association of lumbar facet tropism and orientation with lumbar disc herniation is an issue of concern. OBJECTIVE: To overview the association of lumbar facet tropism and orientation with lumbar disc herniation and to clarify the existing problems. METHODS: The articles related to the association of lumbar facet tropism and orientation with lumbar disc herniation published between January 1967 and January 2017 were retrieved from CNKI and PubMed databases by computer. The keywords were “lumbar facet joints, lumbar disc herniation, facet orientation and tropism” in Chinese and English, respectively. Totally 42 articles were enrolled based on the inclusion and exclusion criteria. RESULTS AND CONCLUSION: (1) The association of lumbar facet tropism and orientation with lumbar disc herniation remains unclear. The relationship between the orientation of lumbar disc herniation and lumbar facet tropism is also controversial. (2) The main problems to drive controversy are: inappropriate control group and lacking normal lumbar facet tropism and orientation data; the large age range of subjects;the uncertain standard of measuring lumbar facet tropism. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Imaging evaluation for scaphoid fracture: which surgical approach is more effective and safer?   Feng Yan-hua, Cui Ying-tie, Tian Yi-ren, Zhang Fang, Wang Shi-bo, He Ming-zhe 2017, 21 (31):  5072-5077.  doi: 10.3969/j.issn.2095-4344.2017.31.026 Abstract ( 410 )   PDF (1088KB) ( 169 )   Save BACKGROUND: Because of scaphoid irregular shape and the wrist joint and adjacent bones overlap, so the diagnosis and treatment of scaphoid fracture and treatment became so difficult. Which imaging methods hold highest diagnosis rate, and which kind of surgical approaches with less impact on fracture healing are still under discussion. OBJECTIVE: To review the imaging examinations of scaphoid fracture and the research advance in surgical approaches. METHODS: The first author retrieved CJFD and PubMed databases for the literature addressing the imaging examinations and surgical approaches of scaphoid fracture published from 2005 to 2015 with the keywords of “scaphodl bone, fracture, iconography, surgical approach” in Chinese and English, respectively. The old and repetitive articles were excluded, totally 3 021 articles were retrieved. In accordance with inclusion and exclusion criteria, finally 24 eligible articles were included for result analysis. RESULTS AND CONCLUSION: (1) The wrist joint at positions of pronation 60°, supination 45°, oblique and lateral can reveal the scaphoid from different angles on X-ray, which improves the diagnosis rate. At present, CT is the most reliable method, but there is a lack of quantization parameter for evaluating scaphoid fracture, especially for occult fracture. MRI can completely show the structure of scaphoid, even blood supply. Bone scintigraphy possesses a higher diagnosis rate than X-ray and CT examinations. (2) The surgical approaches of scaphoid fracture include volar, dorsal, radiocarpa approaches, but none is ideal. (3) The ideal surgical approach still needs a in-depth study, which can well reveal the scaphoid, achieve good reduction, reduce the damage to the remaining blood supply, confirm the position of scaphoid benifical for internal fixator implantation, and can be minimally invasive and easy to operate.   中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics

Select

Diagnostic value of procalcitonin for articular infection in adults: a meta-analysis Wang Ting-ting, Sun Wei-peng, Liang Shuang, Zhang Gui-yu, Zhou Chi, Zhu Mei-ling 2017, 21 (31):  5078-5084.  doi: 10.3969/j.issn.2095-4344.2017.31.027 Abstract ( 209 )   PDF (1433KB) ( 171 )   Save BACKGROUND: Due to special physiological characteristics, articular infection is difficult to be cured successfully. Early diagnosis is critical for the treatment of articular infection, thereafter, searching for a biomarker with high sensitivity and specificity is necessary. OBJECTIVE: To systematically evaluate the value of procalcitonin for diagnosing joint infection in adult． METHODS: A computer-based online research was performed for the literature in PubMed, EMbase, the Cochrane Library and CNKI databases from 1990 to June 2017. Literature screening and data extraction were conducted by two reviewers independently according to the inclusion and exclusion criteria. The risk of bias of included studies was assessed by using the Quality Assessment of Diagnostic Accuracy Studies-2. Meta-analysis was then performed using Stata 14.0 software. The pooled weighted sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio were calculated; the summary receiver operating characteristic curve was drawn and the area under the curve was calculated. RESULTS AND CONCLUSION: (1) A total of 10 studies were included, involving 893 patients. (2) The pooled weighted sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio of procalcitonin diagnosing joint infection were 0.82 (95%CI=0.72-0.89), 0.89 (95%CI=0.82-0.93), 7.20 (95%CI=4.6-11.3), 0.20 (95%CI=0.13-0.32), 35 (95%CI=18-71) and 0.92 (95%CI=0.90-0.94), respectively. (3) To conclude, procalcitonin exhibits more diagnostic efficiency for assessing articular infection in adults. 中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程 Figures and Tables | References | Related Articles | Metrics