Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (15): 2431-2435.doi: 10.3969/j.issn.2095-4344.2015.15.026

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Moxibustion therapy for chronic abdominal pain due to irritable bowel syndrome

Bao Chun-hui1, Huang Ren-jia2, Wang Shuo-shuo3, Zhou Zhi-gang4, Hu Zhi-hai3, Zhao Ji-meng2, Wang Si-yao2, Tan Lin-ying1, Liu Shi-min2, Wu Huan-gan1   

  1. 1Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, Shanghai 200030, China
    2Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
    3Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China
    4Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, Jiangxi Province, China
  • Revised:2015-03-24 Online:2015-04-09 Published:2015-04-09
  • Contact: Wu Huan-gan, M.D., Professor, Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, Shanghai 200030, China; Liu Shi-min, M.D., Associate professor, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
  • About author:Bao Chun-hui, M.D., Research assistant, Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, Shanghai 200030, China
  • Supported by:

    the National Basic Research Program of China (973 Program), No. 2015CB554501; the National Natural Science Foundation of China for the Youth, No. 81202752; Shanghai Sailing Program, No. 15YF1411200

Abstract:

BACKGROUND: Chronic visceral pain is one of major complaints of irritable bowel syndrome which seriously affects patient’s quality of life. Recent researches have shown that moxibustion therapy has positive effects on alleviating chronic visceral pain in irritable bowel syndrome patients.
OBJECTIVE: To study the clinical utility of moxibustion in coping with chronic visceral pain of irritable bowel syndrome patients, and shed light on the theoretical basis of moxibustion analgesia, thereby to give insights into the further research and application on moxibustion.
METHODS: With the key words of “moxibustion, irritable bowel syndrome, visceral pain, abdominal pain” in Chinese and in English, respectively, a computer-based search was performed in CNKI, VIP, Wanfang and PubMed databases for articles published from January 1990 to October 2014. After the initial screening, the remained articles went through further selection and categorization.
RESULTS AND CONCLUSION: The result shows promising results of moxibustion on relieving chronic visceral pain for both two subtypes of irritable bowel syndrome patients, diarrhea type and constipation type. Moxibustion may exert an analgesic effect on chronic visceral pain in irritable bowel syndrome patients through regulation of visceral hypersensitivity, gastrointestinal motility disorders, brain-gut axis and neuroendocrine system disorders, immune dysfunction and low-grade inflammation in the gut, psychological abnormalities, and alteration of intestinal flora. However, to fully understand the analgesia effect of moxibustion and elucidate its mechanism, more standardized randomized controlled trials employing advanced scientific techniques and equipments will still be needed in the future.



中国组织工程研究
杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松组织工程


全文链接:

Key words: Irritable Bowel Syndrome, Abdominal Pain, Moxibustion, Analgesia

CLC Number: