Repetitive magnetic stimulation of S3 nerve root and M1 area for treating urinary retention after spinal cord injury

doi:10.12307/2024.274

Abstract

Abstract: BACKGROUND: Repetitive magnetic stimulation of either S3 nerve root or M1 area can improve the urination function of patients with urinary retention after spinal cord injury, but there are few reports on the repetitive magnetic stimulation of both sites in patients with urinary retention after spinal cord injury.
OBJECTIVE: To observe the effect of repetitive magnetic stimulation of both S3 nerve root and M1 area on urinary retention after spinal cord injury.
METHODS: Forty patients with urinary retention after spinal cord injury were enrolled and were randomly divided into two groups (n=20 per group): group A (repetitive magnetic stimulation in both S3 nerve root and M1 area) and group B (repetitive magnetic stimulation in the S3 nerve root and sham stimulation in the M1 area). Patients in both groups were given 4-week repetitive magnetic stimulation based on conventional bladder function intervention. The stimulation time and duration of treatment were same in both groups, with a treatment time of 21 minutes daily, 5 days per week, for 4 weeks in total. The urination diary and urodynamics were compared between two groups.
RESULTS AND CONCLUSION: Before treatment, there were no statistically significant differences in the average daily catheterization times, average daily catheterization volume, average single urinary volume, urinary storage period (maximum bladder volume, bladder pressure), and urinary voiding period (detrusor pressure, residual urine volume) between the two groups (P > 0.05). After 4 weeks of treatment, the average daily catheterization times in group A were lower than before treatment (P < 0.05), while the average single urination volume in group A was higher than that before treatment (P < 0.05); and the average daily catheterization times in group B were lower than before treatment (P < 0.05). After 4 weeks of treatment, the average daily catheterization times in group A were lower than those in group B, and the average single urination volume was higher than that in group B (P < 0.05). After 4 weeks of treatment, the maximum bladder volume and detrusor pressure during urination were increased in both groups compared with before treatment (P < 0.05), while the bladder pressure and residual urine volume at the maximum volume of the two groups were decreased compared with those before treatment (P < 0.05). Compared with group B, the maximum bladder volume and detrusor pressure during urination were higher in group A, while the bladder pressure and residual urine volume at maximum volume were lower in group A (P < 0.05). To conclude, two treatments can both improve the urination function of patients with urinary retention after spinal cord injury, and repetitive magnetic stimulation of both S3 nerve root and M1 area is superior to repetitive magnetic stimulation of S3 nerve root alone. Repetitive magnetic stimulation of both S3 nerve root and M1 area can effectively improve the urination function of patients with urinary retention after spinal cord injury.

Key words: spinal cord injury, urinary retention, repetitive magnetic stimulation, urodynamic examination, urination function, bladder pressure

CLC Number:

Xu Zihan, Bi Yunfeng, Li Jiang, Zhang Zongliang, Song Chen, Dong Jie, Liu Dong. Repetitive magnetic stimulation of S3 nerve root and M1 area for treating urinary retention after spinal cord injury[J]. Chinese Journal of Tissue Engineering Research, 2024, 28(11): 1719-1723.

Figures/Tables 5

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