Treatment of Achilles tendinitis with an ultrasonic device for emulsification

doi:10.12307/2022.492

Abstract

Abstract: BACKGROUND: At present, conservative and surgical treatments are difficult to cure tendinitis. A minimally invasive and convenient treatment has not been widely used in clinical practice.
OBJECTIVE: To explore the feasibility of applying ultrasonic emulsification device to treat Achilles tendinitis in a rabbit model of Achilles tendinitis.
METHODS: Thirty New Zealand rabbits were randomized into a control group, a model group and an ultrasonic emulsification group. A model of Achilles tendinitis was built in the model and ultrasonic emulsification groups by collagenase injection. Rabbits in the control and model groups were only given normal saline, while those in the ultrasonic emulsification group were subjected to ultrasonic emulsification under guidance of B-mode ultrasonic scan within at 3 weeks after modeling. Three weeks after treatment, tendon repair was estimated by biomechanical analysis, hydroxyproline concentration measurement, and hematoxylin-eosin staining of the tendon tissue.
RESULTS AND CONCLUSION: Three weeks after ultrasonic emulsification treatment, hematoxylin-eosin staining showed that the disordered arrangement of collagen fibers and the cell condensation were improved compared with the model group, while the biomechanical analysis and hydroxyproline concentration showed no relief in tendinitis. Therefore, ultrasonic emulsification treatment has an application prospect in tendon repair; however, it is necessary to further explore and optimize the treatment parameters and modes to improve the therapeutic effect in many aspects.

Key words: ultrasonic emulsification, tendinitis, biomechanics, minimally invasive, treatment, rabbit

CLC Number:

Yang Xiaoxiao, Xu Yuanjing, Li Wentao, Wang Wenhao, Ma Zhenjiang, Wang Jinwu. Treatment of Achilles tendinitis with an ultrasonic device for emulsification[J]. Chinese Journal of Tissue Engineering Research, 2022, 26(14): 2259-2264.

Figures/Tables 6

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