Chinese Journal of Tissue Engineering Research ›› 2020, Vol. 24 ›› Issue (2): 187-191.doi: 10.3969/j.issn.2095-4344.1914

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Uniaxial quasi-static tensile properties of articular cartilage with crack defects

Si Yunpeng1, 2, Gao Lilan1, 2, Zhang Chunqiu1, 2, Peng Yulin3   

  1. 1Key Laboratory of Advanced Electromechanical System Design and Intelligent Control, Tianjin University of Technology; 2National Experimental Teaching Demonstration Center of Mechatronics Engineering, Tianjin University of Technology; 3the Second Etching Division, Beijing North Huachuang Microelectronics Equipment Co., Ltd.
  • Received:2019-05-23 Revised:2019-05-28 Accepted:2019-06-29 Online:2020-01-18 Published:2019-12-25
  • Contact: Gao Lilan, PhD, Professor, Key Laboratory of Advanced Electromechanical System Design and Intelligent Control, Tianjin University of Technology, Tianjin 300384, China; National Experimental Teaching Demonstration Center of Mechatronics Engineering, Tianjin University of Technology, Tianjin 300384, China
  • About author:Si Yunpeng, Master candidate, Key Laboratory of Advanced Electromechanical System Design and Intelligent Control, Tianjin University of Technology, Tianjin 300384, China; National Experimental Teaching Demonstration Center of Mechatronics Engineering, Tianjin University of Technology, Tianjin 300384, China
  • Supported by:
    the National Natural Science Foundation of China, No. 11572222 and 11672208; the Key Project of the Natural Science Foundation of Tianjin, No. 18JCZDJC36100

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Abstract:

BACKGROUND: Once the articular cartilage has a crack defect, its mechanical properties will change. In previous studies, the investigation of damaged articular cartilage mostly focused on compression, and there were few studies on tensile properties.

OBJECTIVE: To measure the uniaxial quasi-static tensile properties by preparing crack defects on the cartilage layer samples.

METHODS: The articular cartilage of the fresh adult pig knee joint was selected to prepare a cartilage specimen containing a crack defect. The tensile properties were tested at different stress rates (0.001, 0.01 and 0.1 MPa/s) and the creep properties were tested under different constant stresses (1, 2 and 3 MPa).

RESULTS AND CONCLUSION: (1) In the tensile test at different stress rates, as the stress rate increases, the stress required to reach the same strain increased gradually, and the Young’s modulus of the test piece increases with the increase of the stress rate. (2) The tensile stress-strain curves of the articular cartilage with cracks at different stress rates did not coincide, indicating that the tensile properties of the articular cartilage with crack defects are rate-dependent. (3) In the creep experiment under different constant tensile stress levels, the creep strain increased with the increase of the tensile stress level, the creep compliance decreased with the increase of the tensile stress level, and with the creep time. The creep strain increased rapidly and then increased slowly. (4) To conclude, different stress rates and different constant stresses have great influence on the tensile mechanical properties of articular cartilage with crack defects. The experimental results provide a mechanical reference for the repair of defective articular cartilage.

Key words: crack defect, articular cartilage, uniaxial stretching, stress rate, constant stress, creep, biomechanics, tissue engineering

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