Chinese Journal of Tissue Engineering Research ›› 2018, Vol. 22 ›› Issue (22): 3569-3574.doi: 10.3969/j.issn.2095-4344.0892

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Uroflowmeter calibration device: standard water flow and its stability

Wang Li-xin1, 2, Ji Jun1, 2, Gao Jia-shuo2, Xiao Hong2   

  1. 1College of Biomedical Engineering, Southern Medical University, Guangzhou 510515, Guangdong Province, China; 2Medical Engineering Department of the 305th Hospital of PLA, Beijing 100017, China
  • Received:2018-02-07 Online:2018-08-08 Published:2018-08-08
  • Contact: Ji Jun, Chief technician, College of Biomedical Engineering, Southern Medical University, Guangzhou 510515, Guangdong Province, China; Medical Engineering Department of the 305th Hospital of PLA, Beijing 100017, China
  • About author:Wang Li-xin, Master candidate, College of Biomedical Engineering, Southern Medical University, Guangzhou 510515, Guangdong Province, China; Medical Engineering Department of the 305th Hospital of PLA, Beijing 100017, China
  • Supported by:

    the Military Metrology Establishment Project, No. 2016[599]; the Military Medical Measurement Research Project, No. 2012-JL1-016

Abstract:

BACKGROUND: As the gear pump’s leakage and pulsation are not taken into account to the design of the uroflowmeter calibration device composed of digital signal processor (DSP) and gear pump, a wrong result will be produced if we just calibrate the urinary flow meter with the theory flow data that work out by the recorded data of the gear pump’s rotate speed.

OBJECTIVE: Based on the designed uroflowmeter calibration device, using DSP timer to control the operation time of the gear pump to obtain a standard water flow with fixed rate and quantity, to measure the quantities of each standard water flow and to analyze the measurement results in order to test if the standard water flows produced by the uroflowmeter calibration device are suitable to calibrate urine flow rate in clinic.
METHODS: The quantity of each standard water flow was measured by B2000S scales in different time by different experimenters. SPSS 20.0 software was then used to draw the distribution histogram of each standard water flow measurement results. We also analyzed the factors affecting the uncertainty of the measurement results, and calculated the uncertainty of the results by systematic analysis.

RESULTS AND CONCLUSION: (1) The quantities of each standard water flow measured by different experimenters in different time were consistent with normal distribution. The maximum stand deviation was 0.549 mL at the flow rate of 15 mL/s, and the minimum stand deviation was 0.147 mL at the flow rate of 10 mL/s. This indicates that the standard water flow produced by the uroflowmeter calibration device has a very high stability, both in flow rate and in flow volume. Therefore, the mean value of the multiple measurement results can be used as the best estimated value of the standard water flow. (2) The uncertainty of the measurement results were calculated by systematic analysis. The uncertainty was 0.75 mL in maximum at the rate of 50 mL/s, and 0.29 mL in minimum at the rate of 10 mL/s, which meets the requirement that the maximum rate between the uncertainties of a standard device and a calibrated device is less than 1:3. Therefore, the uroflowmeter calibration device can be used to calibrate urine flow rate in clinical practice.

中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程

Key words: Urodynamics, Calibration, Tissue Engineering

CLC Number: