Polypropylene versus polyester patches for inguinal hernia repair: pain relief and changes in plasma superoxide dismutase and malondialdehyde levels

doi:10.3969/j.issn.2095-4344.0774

Abstract

Abstract:

BACKGROUND: Polyester and polypropylene patches are commonly used patch materials for inguinal hernia repair. Both of them have their own characteristics.

OBJECTIVE: To observe and compare the effects of different patches on plasma superoxide dismutase and malondialdehyde levels as well as pain relief in male inguinal hernia patients.

METHODS: One hundred and twenty male patients with inguinal hernia were divided into three groups (n=40 per group): a control group treated with traditional hernia repair surgery, a polypropylene patch group and a polyester patch group treated with tension-free hernia repair using polypropylene or polyester patches. Operation time, hospitalization time, patch fixation time, time for urinary catheter removal, and bed time were recorded. Visual Analogue Scale was used for pain assessment before and 12, 24, 48, 72 hours after repair. Plasma levels of superoxide dismutase and malondialdehyde were detected before and 1, 2, 7 days after repair.

RESULTS AND CONCLUSION: Compared with the control group, the operation time, hospitalization time and bed time were shorter in the polyester and polypropylene patch groups (P < 0.05), but there was no significant difference in the time for removal of urinary catheters among the three groups. Moreover, there was also no significant difference in the patch fixation time between the two patch groups. The Visual Analog Scale scores in the three groups were all significantly decreased at 12, 24, 48, 72 hours after repair with the baseline data (P < 0.05), while there was no significant difference among the three groups. At postoperative 1, 2, 7 days, the plasma level of superoxide dismutase was significantly lower in the polyester patch group than the polypropylene patch group (P < 0.05), while the level of malondialdehyde was ranked as follows: polyester patch group > polypropylene patch group > control group (P < 0.05). These findings indicate that both traditional hernia repair and tension-free hernia repair can significantly relieve the pain of male inguinal hernia patients. Patch implantation can change the plasma levels of superoxide dismutase and malondialdehyde in patients with inguinal hernia; in contrast, the polypropylene patch only results in a little effect on the levels.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Tissue Engineering, Hernia, Inguinal, Free Radicals

CLC Number:

R318

Zheng Bing, Wang Wei, Ren Rui, Zhu Tao, Lu Ling-jun, Lu Chang-you . Polypropylene versus polyester patches for inguinal hernia repair: pain relief and changes in plasma superoxide dismutase and malondialdehyde levels[J]. Chinese Journal of Tissue Engineering Research, doi: 10.3969/j.issn.2095-4344.0774.

Figures/Tables 6

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