Anesthetic effect of different concentrations of low-dose hypobaric ropivacaine in elderly knee or hip replacement

doi:10.3969/j.issn.2095-4344.2017.15.008

Abstract

Abstract:

BACKGROUND: Unilateral spinal epidural anesthesia with ropivacaine can reduce the perioperative pain in the elderly undergoing hip or knee arthroplasty, but choosing which concentration of small dose hypobaric ropivacaine is an issue of concern.

OBJECTIVE: To explore the anesthetic and analgesic effects of unilateral spinal epidural anesthesia with different concentrations of low dose hypobaric ropivacaine in senile knee or hip replacement.

METHODS: Ninety patients undergoing knee or hip replacement in the Henan Province Hospital of TCM from August 2014 to December 2015 were enrolled, and randomized into 0.15%, 0.5% and 0.25% ropivacaine groups (n=30 per group), followed by spinal epidural anesthesia at L_3-4or L_2-3 lumbar interspace, respectively.

RESULTS AND CONCLUSION: (1) The order of the flat subsided time and motor block recovery time was as follows: 0.15% ropivacaine group < 0.25% ropivacaine group < 0.5% ropivacaine group; the onset time of motor block was longest in the 0.25% ropivacaine group, followed by 0.5% ropivacaine group, and shortest in the 0.15% ropivacaine group (all P < 0.05). (2) The order of the visual analogue scale scores at 1, 5, and 10 hours after anesthesia and 24 hours postoperatively was as follows: 0.5% ropivacaine group < 0.25% ropivacaine group < 0.15% ropivacaine group (P < 0.05). (3) The change levels of heart rate and blood pressure were highest in the 0.5% ropivacaine group, followed by 0.15% ropivacaine group, and lowest in the 0.25% ropivacaine group. (4) The incidence of adverse events was highest in the 0.5% ropivacaine group, followed by 0.15% ropivacaine group, and lowest in the 0.25% ropivacaine group (P < 0.05). (5) To conclude, 3 mL of 0.25% ropivacaine exhibits desired anesthetic effect.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Anesthesia, Arthroplasty, Replacement, Tissue Engineering

CLC Number:

R318

Pang Liu-cheng, Zhao Feng, Yang Jian-sheng, Zhao Yan-fen. Anesthetic effect of different concentrations of low-dose hypobaric ropivacaine in elderly knee or hip replacement [J]. Chinese Journal of Tissue Engineering Research, 2017, 21(15): 2336-2341.

Figures/Tables 5

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