Application of degradable high-purity magnesium screw in the treatment of developmental dysplasia of the hip

doi:10.12307/2022.081

Abstract

Abstract: BACKGROUND: In the selection of total hip arthroplasty for acetabular defect patients with developmental dysplasia of the hip, the management of the acetabular side is very important for the placement of the prosthesis. The external and upper acetabular bone grafting has been proven to be a safe and feasible treatment method, and how to carry out the bone grafting has become the key factor for the success of the operation.
OBJECTIVE: To investigate the clinical effect of external and superior acetabular bone graft combined with total hip arthroplasty in the treatment of acetabular defect in patients with developmental dysplasia of the hip and fixation of bone graft with degradable high-purity magnesium metal screws.
METHODS: Seven cases of developmental dysplasia of the hip acetabulum defect patients, with 1 male and 6 females, aged 54-65 years, were included from the Affiliated Zhongshan Hospital of Dalian University. According to Crowe type, there were 2 cases of I type, 1 case of II type, 2 cases of III type, and 2 cases of IV type. All cases underwent artificial total hip arthroplasty. The acetabulum received external and upper acetabular bone grafting and the coverage. The bone grafts were fixed with biodegradable high-purity magnesium metal screw. The imaging examination, Harris hip functional score and visual analogue scale score were performed in the postoperative follow-up. This study was approved by the Ethics Committee of the Affiliated Zhongshan Hospital of Dalian University (approval No. 2013-006).
RESULTS AND CONCLUSION: (1) Seven patients were followed up for 2-4.5 years. The shortened affected limb decreased from (2.43±0.78) cm preoperatively to (0.57±0.56) cm postoperatively. No incision infection or nonunion was observed, and no periprosthetic infection was observed. (2) The visual analogue scale score at the last follow-up was lower than that before surgery in seven patients (P < 0.05). Harris score of hip function was higher than that before surgery (P < 0.05). (3) Imaging examination showed that all the degradable high-purity magnesium metal screws were degraded three or four years after surgery, and the graft bone healed with the acetabular bone. No graft loss or prosthesis loosening was observed. No postoperative adverse complications were observed in all cases. (4) The results showed that for the patients with acetabular defect with developmental dysplasia of the hip, the treatment with degradable high-purity magnesium metal screw fixation and total hip arthroplasty on the external and upper part of the acetabulum was satisfactory in the short term.

Key words: developmental dysplasia of the hip, total hip arthroplasty, acetabulum defect, biological prosthesis, metal bone nail, magnesium, magnesium screw

CLC Number:

Huang Shibo, Xie Hui, Wang Zongpu, Wang Weidan, Qin Kairong, Zhao Dewei. Application of degradable high-purity magnesium screw in the treatment of developmental dysplasia of the hip[J]. Chinese Journal of Tissue Engineering Research, 2022, 26(4): 493-498.

Figures/Tables 4

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