Chinese Journal of Tissue Engineering Research ›› 2016, Vol. 20 ›› Issue (30): 4503-4508.doi: 10.3969/j.issn.2095-4344.2016.30.014

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 Use of the Y-shaped mesh in functional repair of the pelvic floor in women

Zhang Yu-di, Lu Dan, Zheng Ping, Wu Xia, Li Hui, Liu Ju-hong   

  1. Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China
  • Received:2016-05-08 Online:2016-07-15 Published:2016-07-15
  • Contact: Lu Dan, Chief physician, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China
  • About author:Zhang Yu-di, Master, Associate chief physician, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China

Abstract:

BACKGROUND: The Y-shaped mesh graft material weaved using lightweight polypropylen has the appropriate porosity, which not only can make the vaginal tissues grow and fuse rapidly on the mesh, but also can maintain good biological strength to ensure the fixed strength for the presacral suspension.
OBJECTIVE: To retrospectively analyze the clinical effect of Y-shaped mesh for the biological function reconstruction of the female pelvic floor.
METHODS: Ten female cases of pelvic floor dysfunction were enrolled, aged 37-73 years, and all were given the treatment of sacral colposuspension under laparoscopy. Then perioperative complications were recorded; patients were followed up regularly to record the Pelvic Organ Prolapse Quantification (POP-Q) score at different time points; and the subjective satisfaction was investigated using the Pelvic Floor Impact Questionnaire (PFIQ-7).
RESULTS AND CONCLUSION: After at least 6-month follow-up, no postoperative pelvic infection, nerve damage and complications appeared, the patients healed well, and no mesh erosion, infection and other adverse reactions occurred. The POP-Q and PFIQ-7 scores at 1, 3 and 6 months after repair were significantly improved than those before repair (P < 0.05). These results suggest that the Y-shaped biological mesh repairing female midpelvic floor dysfunction has good biocompatibility, and can restore the anatomy of the pelvic floor.

中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程

Key words: Pelvic Organ Prolapse, Pelvic Floor, Tissue Engineering

CLC Number: