Mechanical properties of vascularized patellar tendon graft

doi:10.3969/j.issn.2095-4344.2015.47.024

Abstract

Abstract:

BACKGROUND: The clinical study on the mechanical properties of biomaterials for cruciate ligament reconstruction is of great importance, which can provide a theoretical basis for the clinical development of materials with good structure, biomechanics and compatibility.
OBJECTIVE: To analyze the mechanical properties of vascularized patellar tendon graft.
METHODS: The anterior cruciate ligaments of the left foreleg from 42 New Zealand white rabbits were cut off. Then, these rabbits were randomly and evenly divided into two groups: experimental group and control group. Rabbits in the experimental group were implanted vascularized patellar tendon graft for anterior cruciate ligament repair. Rabbits in the control group were implanted with autologous non-vascularized patellar tendon graft for anterior cruciate ligament repair. At the 8th, 12th and 16th weeks after implantation, biomechanical properties of specimens from these two groups were detected.
RESULTS AND CONCLUSION: There was no significant difference on the fracture location at different time points between these two groups; at the 12th and 16th weeks after transplantation, the knee laxity in the experimental group was higher than that in the control group (P < 0.05). At the 8th week after transplantation, there was no significant difference in the knee laxity between these two groups. At the 8th, 12th and 16th weeks after transplantation, the maximum load in the experimental group was higher than that in the control group (P < 0.05). At the 8th, 12th and 16th weeks after transplantation, the stiffness in the experimental group was higher than that in the control group (P < 0.05). There was no significant difference in the maximum tensile elongation between these two groups at different time points after transplantation. These results demonstrate that vascularized patellar tendon graft has good mechanical properties.
中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Transplants, Anterior Cruciate Ligament, Biomechanics, Tissue Engineering

Xu Chang, Ma Qiang, Aierxiding, Wang Xiao-ting, Shen Zhi-min . Mechanical properties of vascularized patellar tendon graft[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(47): 7676-7680.

Figures/Tables 5

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