Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (34): 5438-5442.doi: 10.3969/j.issn.2095-4344.2015.34.006

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Apexification of immature permanent teeth with calcium hydroxide paste 

Nie Er-min1, Lu Jie2, Jiang Rui1, Zhang Chun-yuan1, Zeng Jin-di1, Tan Ji-zhou1   

  1. 1Department of Stomatology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China; 2Department of Stomatology, the Second Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510095, Guangdong Province, China
  • Online:2015-08-20 Published:2015-08-20
  • Contact: Zhang Chun-yuan, Master, Professor, Department of Stomatology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China
  • About author:Nie Er-min, Master, Attending physician, Department of Stomatology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China

Abstract:

BACKGROUND: Preparation of calcium hydroxide paste for apexification of immature permanent teeth has recently achieved satisfactory clinical efficacy because of its advantages including simple-to-use, being well proportioned and full contact with dentin and root apical periodontal tissues after being guided into root canal. 

OBJECTIVE: To validate the clinical efficacy of apexification of immature permanent teeth with calcium hydroxide paste. 

METHODS: Thirty-four patients with periapical periodontitis caused by fracture of abnormal central cusp, consisting of 18 males and 16 females, aged 8-12 years, were included and they received apexification with calcium hydroxide paste. X-ray observation of the tooth apex was performed at 1, 3, 6, 12 and 24 months after operation.

RESULTS AND CONCLUSION: Among the 34 cases, 32 cases were successful and 2 cases failed in apexification of immature permanent teeth with calcium hydroxide paste, the success rate was 94%. 16 cases had apical closure at 9-12 months, 15 cases finished apexification at 12-15 months, 1 case with severe infection finished induction at 18-21 months, and two cases could not finish induction at 24 months. During 2 years of follow-up period, there were no recurrence of periapical periodontitis, tooth loose and shedding, tooth fracture, root progressive absorption and other complications. All the teeth had type II apical closure, and there were no type I and IV apical closure, and the rare cases had the type between II and III which was difficult to distinguish. Apexification with calcium hydroxide paste for immature permanent teeth with incomplete developed root can preserve the affected teeth, alleviate inflammation, and show good induction effects.

中国组织工程研究杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松组织工程

Key words: Apexification, Periapical Periodontitis

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