Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (16): 2588-2592.doi: 10.3969/j.issn.2095-4344.2015.16.024

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Packing effects of different hemostatic materials during functional endoscopic sinus surgery: histocompatibility comparison

Guo Li-ping1, Wang Dong2, Li Tong-li2   

  1. 1Department of ENT, Shouyang People’s Hospital, Jinzhong 045400, Shanxi Province, China; 2ENT & HN Surgery Department, Shanxi Provincial People’s Hospital, Taiyuan 036200, Shanxi Province, China
  • Received:2015-04-06 Online:2015-04-16 Published:2015-04-16
  • Contact: Wang Dong, Chief physician, Professor, Master’s supervisor, ENT & HN Surgery Department, Shanxi Provincial People’s Hospital, Taiyuan 036200, Shanxi Province, China
  • About author:Guo Li-ping, Associate chief physician, Department of ENT, Shouyang People’s Hospital, Jinzhong 045400, Shanxi Province, China

Abstract:

BACKGROUND: At present, the most common materials for clinical hemostasis are absorbable tampons and Vaseline gauze.
OBJECTIVE: To compare the packing effects of absorbable tampons and Vaseline gauze in functional endoscopic sinus surgery.  
METHODS: Totally 100 sinusitis patients, 57 males and 43 females, aged 16-61 years, with a history of 5 months to 23 years, were randomized into two groups: patients in the observation group were treated with absorbable tampons and patients in the control group treated with Vaseline gauze during functional endoscopic sinus surgery. Patient’s discomfort, bleeding when the filler was extracted at 48 hours, and nasal bleeding within postoperative 24 hours were compared between the two groups.  
RESULTS AND CONCLUSION: No adverse reaction related to absorbable tampons occurred in the observation group, indicating that the absorbable tampon has better histocompatibility. Patient’s discomfort, bleeding when the filler was extracted at 48 hours after operation, and nasal bleeding within postoperative 24 hours were significantly improved in the observation group compared with the control group (P < 0.05). These findings suggest that the absorbable tampons has a better hemostatic function, which can effectively reduce postoperative nasal bleeding and relieve postoperative discomfort in patients with sinusitis.


中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程


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Key words: Biocompatible Materials, Hemostasis, Endoscopic, Sinusitis

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