Chinese Journal of Tissue Engineering Research ›› 2026, Vol. 30 ›› Issue (21): 5524-5533.doi: 10.12307/2026.777
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Li Kanglin, Gao Shihua, Jiang Yongdong, Huang Ziqi, Wu Yufeng
Accepted:2025-09-02
Online:2026-07-28
Published:2026-03-05
Contact:
Wu Yufeng, MS, Master’s supervisor, Professor, Chief physician, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine, Zhongshan 528400, Guangdong Province, China
About author:Li Kanglin, Master candidate, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine, Zhongshan 528400, Guangdong Province, China
Supported by:CLC Number:
Li Kanglin, Gao Shihua, Jiang Yongdong, Huang Ziqi, Wu Yufeng. Arthroscopy-assisted loop titanium plate versus clavicular hook plate for acute acromioclavicular joint dislocation: clinical efficacy and cost-effectiveness[J]. Chinese Journal of Tissue Engineering Research, 2026, 30(21): 5524-5533.
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2.1 参与者数量分析 纳入急性 Ⅲ-Ⅴ型肩锁关节脱位患者80例,依据手术方式的不同分为带袢钛板组和钩钢板组,每组40 例。在研究进程中,部分患者因多种原因未能完成随访,最终进入结果分析的患者共 64 例,其中带袢钛板组31例,钩钢板组33例。 带袢钛板组脱落9例,具体原因如下:4 例患者在随访过程中失联,可能是由于患者更换联系方式后未及时告知研究团队,或因工作、生活变动等因素导致无法追踪;3例患者明确拒绝复查,因对复查流程存在抵触情绪或时间安排冲突等导致脱落;另有2例为其他原因,包括患者因严重基础疾病需优先治疗其他病症,以及因居住地变迁距离研究中心过远而放弃继续参与随访。 钩钢板组脱落7例,其中2例发生二次创伤,由于术后康复期间防护不当,导致肩部再次受损,从而影响了后续随访的进行;3例患者失联,原因与带袢钛板组失联患者类似,主要涉及联系方式变更和追踪困难;2例患者转院治疗,都因个人原因选择到其他医疗机构接受进一步诊治,进而退出了此次研究的随访。 2.2 试验流程图 见图7。"
2.6 两组术后并发症情况 带袢钛板组术后感染、肩锁关节疼痛、内固定松动总发生率低于钩钢板组(P < 0.05)。对于术后感染患者,行抗生素抗感染治疗;对于肩锁关节疼痛者,予以口服止痛药,配合外敷药物、推拿、按摩、针灸、理疗等方法来缓解;对于内固定松动严重者,必要时考虑二次手术。见表8。 2.7 植入物与宿主的生物相容性 带袢钛板组术后未出现植入物周围感染、过敏反应、免疫反应及排斥反应,但发生2例原因不明的肩锁关节疼痛,经过一系列的药物理疗手段,最终患者疼痛缓解。分析疼痛原因,推测可能与术后组织修复过程中的炎症反应以及个人疼痛敏感程度有关。 锁骨钩钢板组术后出现1例植入物周围感染,但未出现明确的过敏反应、免疫或排斥反应。此外,还存在2例原因不明的肩锁关节疼痛和1例内固定松动,其中感染可能与手术创伤、术后护理相关,而非植入物本身的生物相容性问题。 综上,两种植入物在此次研究中均未表现出明显的过敏、免疫排斥等生物相容性相关不良反应。"
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