Chinese Journal of Tissue Engineering Research ›› 2023, Vol. 27 ›› Issue (32): 5168-5172.doi: 10.12307/2023.843
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Maihemutijiang · Muhaimaiti, Maimaitishawutiaji · Maimaiti, Tang Junwei, Zhang Yuxin
Received:
2022-08-10
Accepted:
2022-11-18
Online:
2023-11-18
Published:
2023-03-23
Contact:
Zhang Yuxin, Chief physician, Department of Spinal Orthopedics, the First People’s Hospital of Kashgar, Kashgar 844099, Xinjiang Uygur Autonomous Region, China
About author:
Maihemutijiang · Muhaimaiti, Master, Attending physician, Department of Spinal Orthopedics, the First People’s Hospital of Kashgar, Kashgar 844099, Xinjiang Uygur Autonomous Region, China
Supported by:
CLC Number:
Maihemutijiang · Muhaimaiti, Maimaitishawutiaji · Maimaiti, Tang Junwei, Zhang Yuxin. Has-miR-100-5p targeting zinc finger and BTB domain containing 7A is a potential target for postmenopausal osteoporosis[J]. Chinese Journal of Tissue Engineering Research, 2023, 27(32): 5168-5172.
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2.3 has-miR-100-5p和has-miR-101-3p靶标基因 通过miRTargetbase数据库和miRTarget数据库预测has-miR-100-5p和has-miR-101-3p 的调控靶标基因,并与共同差异表达基因比较。鉴定了has-miR-100-5p和has-miR-101-3p靶向CAMKK2、EIF5A、PIM1、ZBTB7A的调控网络,见图3A。其中,ZBTB7A同时被has-miR-100-5p和has-miR-101-3p所调控,被认为是关键靶标基因。miRTargetbase数据库中预测的ZBTB7A与has-miR-100-5p和has-miR-101-3p的结合位点,见图3B。"
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