Chinese Journal of Tissue Engineering Research ›› 2017, Vol. 21 ›› Issue (10): 1611-1616.doi: 10.3969/j.issn.2095-4344.2017.10.022

Previous Articles     Next Articles

Tissue-engineered scaffold preparation using three-dimensional printing technology: a retrospective study on bone repair

Jin Can, Chen Zhen-qi   

  1. Department of Orthodontics, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong
    University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai 200011, China
  • Received:2016-12-13 Online:2017-04-08 Published:2017-05-08
  • Contact: Chen Zhen-qi, Professor, Department of Orthodontics, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai 200011, China
  • About author:Jin Can, Studying for master’s degree, Department of Orthodontics, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai 200011, China
  • Supported by:

    the Scientific Research Program of the Shanghai Science and Technology Committee, No. 124119b0103

Abstract:

BACKGROUND: The tissue-engineered scaffold, as a substitute of autogenous bone graft, plays an important role in bone repair. In the meanwhile, three-dimensional (3D) printing technology has obtained more attention because of its accurate adjustment.
OBJECTIVE: To review the in vitro or in vivo studies on the 3D-printed scaffolds applied in bone repair, thus providing basis for clinical research.
METHODS: The first author searched the PubMed database using the English keywords of “tissue engineering, bone, three-dimensional printing, scaffold” for pertinent articles addressing 3D-printed tissue-engineered scaffolds.
RESULTS AND CONCLUSION: There are plenty of studies on 3D-printed tissue-engineered scaffolds, and recent research focuses on the material selection and surface modification. The appropriate porosity is vital, and with the development of manufacturing technology, each property of the scaffold is improved, and composite materials prevail gradually. All above improvements enhance the mechanical property and promote cell adhesion and proliferation. Furthermore, the surface modification promotes the implant-bone interaction. In vivo and in vitro research both indicate that composite materials and the surface coating of bone induction can improve the scaffold performance and osteogenesis.

中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程

Key words: Biocompatible Materials, Braces, Alveolar Process, Tissue Engineering

CLC Number: