Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (47): 8775-8778.doi: 10.3969/j.issn.2095-4344.2012.47.008

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Tetracycline-modified calcium-phosphorus colloid: The synthetic material extracted from dental enamel

Deng Wei1, Wei Chun-ping2, Liu Xin-zheng1   

  1. 1Department of Stomatology, 2Department of Otolaryngology, First Affiliated Hospital of Gannan Medical College, Ganzhou 341000, Jiangxi Province, China
  • Received:2012-04-09 Revised:2012-08-05 Online:2012-11-18 Published:2013-03-15
  • About author:Deng Wei★, Master, Associate chief physician, Associate professor, Department of Stomatology, First Affiliated Hospital of Gannan Medical College, Ganzhou 341000, Jiangxi Province, China dwdent2@163.com

Abstract:

BACKGROUND: Although the artificial hydroxyapatite is similar as the structure of inorganic composition of human sclerous tissues, its biological property has determinate difference compared to natural tooth and bone tissue.
OBJECTIVE: To analyze the components and crystal characteristics of the synthetic material extracted from dental enamel.
METHODS: The dental enamel power of clinical orthodontic teeth was collected. The power was treated with acid base, modified by tetracycline and then to form the tetracycline-calcium-phosphorus colloid. There were four groups including Group 1 (the dental enamel power), Group 2 (the dental enamel power+tetracycline), Group 3 (the dental enamel power+tetracycline+chitin) and Group 4 (the dental enamel power+tetracycline+chitin+liquid phase). All of them were detected by X-ray diffraction, infrared spectrum and field emission scan electron microscope. Liquid phase was prepared by 0.125 mol/L NaH2PO4 and 0.125 mol/L Na2HPO4 dissolved in distilled water.
RESULTS AND CONCLUSION: The basic phase composition of apatite changed from the single component to multiple phases after the dental enamel was modified by tetracycline. The crystallinity decreased after the dental enamel extraction was modified by tetracycline; however, the adamantine crystallinity obviously increased after the chitin was added. These findings suggest that the main component of the dental enamel extraction is hydroxyapatite; the crystallographic characteristics of apatite, such as the phase, crystallinity and microconstituenis content has obvious modification after the dental enamel is modified by tetracycline; the crystallinity of apatite modified by tetracycline could increase by adding the chitin.

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