Chinese Journal of Tissue Engineering Research ›› 2020, Vol. 24 ›› Issue (16): 2467-2472.doi: 10.3969/j.issn.2095-4344.2252

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Relationship between unilateral percutaneous kyphoplasty for treating Kummell’s disease and the amount of injected bone cement

Ren Yide1, Zhang Yafeng2, Li Feng1, Gao Hongwen1   

  1. 1Department of Orthopedics, Wuxi Huishan District Hospital of Traditional Chinese Medicine, Wuxi 214000, Jiangsu Province, China; 2Department of Orthopedics, Wuxi Hospital of Traditional Chinese Medicine, Wuxi 214000, Jiangsu Province, China
  • Received:2019-07-23 Revised:2019-07-27 Accepted:2019-09-21 Online:2020-06-08 Published:2020-03-24
  • Contact: Zhang Yafeng, Chief physician, Department of Orthopedics, Wuxi Hospital of Traditional Chinese Medicine, Wuxi 214000, Jiangsu Province, China
  • About author:Ren Yide, Master, Physician, Department of Orthopedics, Wuxi Huishan District Hospital of Traditional Chinese Medicine, Wuxi 214000, Jiangsu Province, China
  • Supported by:
    the National Natural Science Foundation of China, No. 81473693

Abstract:

BACKGROUND: Percutaneous kyphoplasty is an effective method to treat Kummell’s disease, but there is no uniform standard for the amount of injected bone cement.

OBJECTIVE: To investigate the relationship between unilateral percutaneous kyphoplasty for treating Kummell’s disease and the amount of injected bone cement.

METHODS: Totally 35 cases of Kummell’s disease, who were treated in the Wuxi Hospital of Traditional Chinese Medicine from January 2014 to June 2018, were included in this study, including 11 males and 24 females. According to bone cement injection volume, unilateral percutaneous kyphoplasty was performed in two groups: Low volume group (n=16; volume ≤ 3 mL) and conventional quantity group (n=19;  3 mL ≤ volume ≤ 6 mL). The leakage of bone cement was observed during operation. Vertebral body refracture was postoperatively observed. Visual analogue scale and Oswestry dysfunction index were used to evaluate the efficacy of the surgery preoperatively, 2 days postoperatively and at last follow-up. Vertebral kyphotic Cobb’s angle and the height of injured vertebral anterior edge were assessed by imaging. This study was approved by the Ethics Committee of Wuxi Hospital of Traditional Chinese Medicine.

RESULTS AND CONCLUSION: (1) All patients successfully completed the operation, and were followed up for 6-36 months. (2) Visual analogue scale scores and Oswestry dysfunction index of the two groups 2 days after treatment and at final follow-up were significantly lower than those before surgery (P < 0.05). However, there was no significant difference in visual analogue scale scores and Oswestry dysfunction index between the two groups (P > 0.05). (3) Cobb’s angle of vertebral kyphosis and the height of the anterior edge of injured vertebral bodies were significantly improved in the two groups 2 days after treatment and at final follow-up (P < 0.05), but there was no significant difference between the two groups (P > 0.05). (4) In the conventional quantity group, cement leakage occurred in 5 cases and vertebral body refracture occurred in 2 cases. In the low volume group, cement leakage occurred in 1 case and vertebral body refracture occurred in 2 cases. The incidences of bone cement leakage and vertebral body refracture had no significant difference between the two groups (P > 0.05). (5) The results showed that unilateral percutaneous kyphoplasty could effectively relieve pain with different amounts of bone cement in Kummell’s disease, and there was no difference in leakage rate and safety of bone cement.

Key words: Kummell’s disease, bone cement, unilateral percutaneous kyphoplasty, bone cement amount, bone cement leakage, vertebral anterior height, Cobb’s angle, visual analogue scale score, Oswestry disability index

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