Chinese Journal of Tissue Engineering Research ›› 2017, Vol. 21 ›› Issue (23): 3688-3693.doi: 10.3969/j.issn.2095-4344.2017.23.014

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Pedicle screw fixation combined with posterior lumbar interbody fusion for degenerative lumbar spondylolisthesis in the elderly

Chen Kang-wu, Zhang Kai, Chen Hao, Wang Gen-lin, Zhu Xiao-yu, Qian Zhong-lai, Yang Hui-lin   

  1. Department of Orthopedics, the Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China
  • Online:2017-08-18 Published:2017-09-01
  • Contact: Yang Hui-lin, Professor, Chief physician, Doctoral supervisor, Department of Orthopedics, the Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China
  • About author:Chen Kang-wu, Master, Attending physician, Department of Orthopedics, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China
  • Supported by:

    the General Project of the Jiangsu Provincial Natural Science Foundation of the Universities, No. 16KJD320004; the Suzhou Young Science and Technology Project, No. kjxw2014009

Abstract:

BACKGROUND: Whether lumbar spondylolisthesis needs to be treated with reduction remains controversial.

OBJECTIVE: To investigate the clinical effectiveness of pedicle screw fixation combined with posterior lumbar interbody fusion for degenerative lumbar spondylolisthesis in the patients aged more than 70 years old.
METHODS: The clinical data of 30 patients with degenerative spondylolisthesis aged over 70 years old undergoing pedicle screw fixation combined with posterior lumbar interbody fusion were analyzed retrospectively. The Visual Analogue Scale, Oswestry Dysfunction Index and the Japan Orthopedics Association scores were compared and analyzed before and after surgery.
RESULTS AND CONCLUSION: (1) Among 30 patients, 12 were male and 18 female, the average age was (75.1±6.7) years old, and all were followed up for more than 12 months. (2) The postoperative Visual Analogue Scale, Oswestry Dysfunction Index and the Japan Orthopedics Association scores were significantly improved compared with baseline (P < 0.05). According to the Japan Orthopedics Association scores, 3 cases were cured, 24 were significantly effective, and 3 effective. (3) Graft fusion was achieved at all patients, the average fusion time was (5.13±0.65) months. (4) The average operation time was (225.6±23.4) minutes, the average intraoperative blood loss was (470±45.5) mL, and the average follow-up time was (25.8±3.5) months. (5) Six patients presented complications (20%), including one case of dural tear, two cases of paralytic intestinal obstruction, and three transient lower extremity nerve symptoms. (6) These results indicate that if the associated disorders are strictly controlled, pedicle screw fixation combined with posterior lumbar interbody fusion can achieve good surgical results in the treatment of degenerative spondylolisthesis in the elderly.

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程

Key words: Intervertebral Disk Degeneration, Internal Fixators, Tissue Engineering

CLC Number: