Intra-articular injection of synovial mesenchymal stem cells to treat articular cartilage injury

doi:10.3969/j.issn.2095-4344.2015.36.027

Abstract

Abstract:

BACKGROUND: Among various seed cells, synovial mesenchymal stem cells have unique advantages in the repair of articular cartilage injury.

OBJECTIVE: To review the progress of synovial mesenchymal stem cells and its intra-articular injection in the treatment of articular cartilage injury.

METHODS: The first author searched PubMed and CNKI by computer to retrieve articles published from January 2004 to December 2004 using the keywords of “synovial mesenchymal stem cells; intra-articular injection; cartilage repair” in English and Chinese, respectively. Finally, 57 articles were included in result analysis.

RESULTS AND CONCLUSION: It is easy to isolate and culture synovial mesenchymal stem cells, which has great advantages in cartilage repair. What’s more, intra-articular injection therapy for articular cartilage injury is feasible and safe. Intra-articular injection of synovial mesenchymal stem cells is a very promising treatment for cartilage damage, but there are still many problems to be solved in the future.

中国组织工程研究杂志出版内容重点：干细胞；骨髓干细胞；造血干细胞；脂肪干细胞；肿瘤干细胞；胚胎干细胞；脐带脐血干细胞；干细胞诱导；干细胞分化；组织工程

Key words: Synovial Membrane, Mesenchymal Stem Cells, Cartilage Diseases

CLC Number:

R318

Yuan Xiao-long, Bi Sheng-rong, Yu Fang-yuan. Intra-articular injection of synovial mesenchymal stem cells to treat articular cartilage injury [J]. Chinese Journal of Tissue Engineering Research, 2015, 19(36): 5892-5897.

Figures/Tables 1

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