Hip-spine syndrome: pathological base and biomechanics mechanism

doi:10.3969/j.issn.2095-4344.2015.33.023

Abstract

Abstract:

BACKGROUND: Low back pain in patients with hip osteoarthritis can be relieved to some extent after total hip arthroplasty, indicating the changes in limb line of force have obvious effects on low back pain.

OBJECTIVE: To review and analysis the pathological base and biomechanics mechanism of hip-spine syndrome.

METHODS: We retrieved PubMed database and China National Knowledge Infrastructure for related articles published from January 1976 to March 2015. The key words were “low back pain, hip-spine syndrome, hip osteoarthritis, total hip replacement, biomechanics, balance parameters” in English and Chinese, respectively. Repeated studies and unrelated articles were excluded.

RESULTS AND CONCLUSION: A total of 145 articles were retrieved, and finally 62 articles were enrolled in result analysis. In the pathophysiology, tumor necrosis factor-α, interleukin-1β and matrix metalloproteinases play a significant role in the occurrence and development of hip-spine syndrome. As for the biological biomechanics, the spine-pelvic-lower limb balance compensatory process can be the main mechanical mechanism of hip-spine syndrome, and the balance parameters can provide a basis for the diagnosis, treatment and postoperative evaluation of hip-spine syndrome.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

Key words: Low Back Pain, Hip Joint, Osteoarthritis, Biomechanics

CLC Number:

R318

Wang Qiang, Zhao Wen-jie, Zhang Bin, Dai Min. Hip-spine syndrome: pathological base and biomechanics mechanism[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(33): 5371-5377.

Figures/Tables 3

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