Bone, tissue and cell transplantation for fractures of the femoral neck and femoral shaft

doi:10.3969/j.issn.2095-4344.2015.21.027

Abstract

Abstract:

BACKGROUND: Femoral neck fracture combined with femoral shaft fracture as a high-energy injury exhibits some difficulties in its clinical treatment because of bone chips and bone defects. Bone and cell transplantations have been used recently in order to effectively fill the bone defect area.
OBJECTIVE: To explore the therapeutic effect of bone transplantation versus cell transplantation for treatment of femoral neck fracture combined with femoral shaft fracture.
METHODS: A retrospective analysis was performed in patients with femoral neck fracture combined with femoral shaft fracture, who respectively underwent internal fixation with bone transplantation, tissue transplantation and cell transplantation. Perioperative indexes, incidence of complications and Harris scores were observed and compared.
RESULTS AND CONCLUSION: (1) Femoral neck fractures are most commonly classified into Garden type, AO type and Pauwell type. Fracture classification aims to unify standards, which is easy to guide treatment and scientific research. (2) Internal fixation with bone transplantation and tissue transplantation is easy, safe and effective to promote fracture healing and improve hip function, which is an effective way to repair femoral neck fractures with femoral shaft fractures. (3) Compared with autogenous bone graft, allograft transplantation materials as finished products have a variety of sources, and have indications and efficacy similar to non-vascularized bone graft, which are suitable for clinical practice, but long-term effects need to be further
explored. (4) Internal fixation with cell transplantation is simple, reliable and effective for femoral neck fractures with femoral shaft fractures, which provides a new idea to reduce the early incidence of femoral head necrosis.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Femur, Fractures, Bone, Bone Transplantation, Cell Transplantation, Stem Cell Transplantation

CLC Number:

R318

Jia Shi-shuang, Zhang Kun, Li Shuang. Bone, tissue and cell transplantation for fractures of the femoral neck and femoral shaft[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(21): 3424-3428.

Figures/Tables 4

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