Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (16): 2608-2612.doi: 10.3969/j.issn.2095-4344.2015.16.028

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Lumbar spinal implants for degenerative lumbar spondylolisthesis: biocompatibility evaluation

Zhang Zhi-min1, Huo Jian-zhong2   

  1. 1Shanxi Medical University, Taiyuan 030001, Shanxi Province, China; 2Department of Orthopedics, Dayi Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China
  • Received:2015-03-06 Online:2015-04-16 Published:2015-04-16
  • Contact: Huo Jian-zhong, Associate professor, Master’s supervisor, Department of Orthopedics, Dayi Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China
  • About author:Zhang Zhi-min, Studying for master’s degree, Shanxi Medical University, Taiyuan 030001, Shanxi Province, China

Abstract:

BACKGROUND: Spinal internal fixation is widely used in the treatment of lumbar spondylolisthesis, with the purpose of lumbar fusion, reconstruction of lumbar sagittal sequences, relieving spinal cord or nerve root compression.
OBJECTIVE: To review the biocompatibility of lumbar spinal implants applied in the treatment of degenerative lumbar spondylolisthesis.
METHODS: A computer-based retrieval of PubMed and CNKI was performed for relevant articles published from January 2000 to January 2015. The keywords were “biocompatibility, degenerative lumbar spondylolisthesis, implant” in English and Chinese, respectively, which appeared in the title and abstract.
RESULTS AND CONCLUSION: Lumbar spinal implants commonly used include pedicle screws and interbody fusion cages. The fusion cages are mainly classified as biological fusion cage, metal fusion cage, composite fusion cage and absorbable fusion cage. Internal fixation implants made of different materials have different biocompatibilities, but also develop different stabilities. With the development of bionics, 3D printing technology, biomechanics and materials science, lumbar spinal implants will have better biocompatibility, bone substitute capability and biomechanical properties.


中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程


全文链接:

Key words: Biocompatible Materials, Spinal Fusion, Lumbar Vertebrae

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