Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (15): 2394-2398.doi: 10.3969/j.issn.2095-4344.2015.15.019

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Vascular complications during and after renal transplantation

Chen Wei-guo, Zhou Peng, Li Xiao-wei, Zhou Ting-ting, Wang Qing-tang, Wang Liang, Yang Hang, Li Sha-dan   

  1. Department of Urology, General Hospital of Chengdu Military Region, Chengdu 610083, Sichuan Province, China
  • Online:2015-04-09 Published:2015-04-09
  • About author:Chen Wei-guo, Master, Associate chief physician, Department of Urology, General Hospital of Chengdu Military Region, Chengdu 610083, Sichuan Province, China

Abstract:

BACKGROUND: Although the renal transplantation technology has been quite mature, vascular complications during and after transplantation inevitably occur.
OBJECTIVE: To investigate the diagnosis and management of vascular complications during and after renal transplantation. 
METHODS: A retrospective analysis was performed in 11 patients suffering from vascular complications during and after renal transplantation. During the transplantation, there were two cases of arterial anastomotic stenosis, one case of renal vain transverse, three cases of atherosclerosis plaque of the external iliac artery blocking the transplant renal artery, one case of twisted renal vein. After transplantation, there were two cases of extra renal pseudoaneurysm, one case of arterial anastomotic stenosis, and one case of renal artery obstruction.
RESULTS AND CONCLUSION: Two cases of arterial anastomotic stenosis during operation had good recovery, and renal allograft dysfunction occurred after 6 and 11 years, respectively. In the case of renal vain transverse, the renal allograft functioned for 12 years. Among the three cases of atherosclerosis plaque of external iliac artery blocking the transplant renal artery, 1 case presented with renal allograft dysfunction immediately, the other two patients,renal function recovered well during the follow-up of 6 and 2 years respectively. In the case of twisted renal vein, delayed graft function occurred, and the patient died of severe pulmonary infection 1 month later. The renal allograft dysfunction occurred in the two cases of post-transplantation extra renal pseudoaneurysm. The case of post-transplantation arterial anastomotic stenosis was treated by balloon angioplasty and metallic stent placement via femoralartery, and the renal function became normal during 18 months of follow-up. The case of post-transplantation renal artery obstruction appeared to have delayed graft function, and died of severe pulmonary infection 3 weeks later. These findings indicate that patients with vascular complications during and after renal transplantation can obtain satisfactory outcomes if receiving accurate diagnosis and timely treatment.



中国组织工程研究
杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松组织工程


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Key words: Kidney Transplantation, Blood Vessels, Renal Insufficiency

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