Medical polyethylene glycol berberine via shoulder joint injections for the treatment of subacromial impingement syndrome: a follow-up of 6 months

doi:10.3969/j.issn.2095-4344.2015.12.016

Abstract

Abstract:

BACKGROUND: Medical polyethylene glycol berberine is a biomaterial against tissue adhesion, with anti-inflammatory effects, which can prevent scar formation and reduce local inflammation.
OBJECTIVE: To observe the clinical efficacy of medical polyethylene glycol berberine via shoulder joint injections on subacromial impingement syndrome.
METHODS: Forty patients with subacromial impingement syndrome I, II were voluntarily divided into two groups: biomaterial group (n=20), single intra-articular injection of 3 mL medical polyethylene glycol berberine; conservative treatment group (n=20), single subacromial space closed treatment of betamethasone combined with lidocaine hydrochloride followed by oral administration of celecoxib 200 mg once, twice a day, totally for 1 week. Patients were followed up clinically for visual analog scale scores, range of motion of the shoulder and the American Shoulder and Elbow Surgeons scores.
RESULTS AND CONCLUSION: Both of two groups had a great improvement in visual analog scale scores, range of motion of the shoulder and the American Shoulder and Elbow Surgeons scores after treatment(P < 0.05), and these scores were improved more significantly in the biomaterial group than the conservative treatment group at 2 weeks, 4 weeks, 3 months, 6 months after treatment (P < 0.001). These findings indicate that the intra-articular injection of medical polyethylene glycol berberine for subacromial impingement syndrome can effectively alleviate shoulder pain, improve shoulder mobility, and promote functional recovery of the shoulder.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

全文链接：

Key words: Polyethylene Glycols, Berberine, Shoulder Impingement Syndrome

CLC Number:

R318

Wang Li-qin, Pan Suo-hua, Chen Yue-ying, Wu Jun. Medical polyethylene glycol berberine via shoulder joint injections for the treatment of subacromial impingement syndrome: a follow-up of 6 months[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(12): 1889-1893.

Figures/Tables 8

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