Biomechanical changes following expanded skin grafting

doi:10.3969/j.issn.2095-4344.2013.07.009

Abstract

Abstract:

BACKGROUND: A skin soft tissue dilator is implanted into the normal skin, generating pressure to expand the skin soft tissue to produce “extra” skin soft tissues by increasing the capacity within the dilator. This technique has become a basic method in skin tissue engineering.
OBJECTIVE: To establish a dog model of expanded skin grafting and to observe the short-term and long-term regular patterns following skin expansion and grafting.
METHODS: Twelve adult dogs were randomly selected. Four dilators of 150 mL, two of which did not work as controls, were implanted into the back of dogs. Skin stress-strain, stress relaxation, and ultimate tensile strength were detected and compared at different periods after skin expansion.
RESULTS AND CONCLUSION: The skin viscoelasticity and intensity reduced significantly after skin expansion. The viscoelasticity could restore the normal value within 6 months, and the intensity, however, had a slower recovery. As biomechanical changes occur provisionally and can be restored after skin grafting, a more attention should be paid in clinic.

Key words: tissue construction, tissue construction and biomechanics, skin grafting, biomechanics, skin viscoelasticity, dilator, skin stress, stress relaxation, tensile strength

CLC Number:

R318

Tian Bao-xiang, Liu Feng-bin, Yang Xiong, Lin Hai-long, Liu Yang, Fan Hua, Wei Chun-lin. Biomechanical changes following expanded skin grafting[J]. Chinese Journal of Tissue Engineering Research, 2013, 17(7): 1185-1188.

Figures/Tables 3

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