Pulse radiofrequency combined with regular calcium supplement in the treatment of thoracic and back pain caused by osteoporotic vertebral compression fractures

doi:10.3969/j.issn.2095-4344.1455

Abstract

Abstract:

BACKGROUND: Thoracic and dorsal pain caused by osteoporotic vertebral compression fractures is very common in clinic. Conventional treatment methods include medicine, physiotherapy, calcium supplement and local nerve block. They all have certain therapeutic effects, but the pain recurs shortly after drug withdrawal. As a technique for treating this kind of pain, pulsed radio frequency has a remarkable short-term effect, but it lacks standardized treatment for osteoporosis, and its long-term effect is not good.

OBJECTIVE: To investigate the therapeutic effect of pulsed radio frequency combined with guideline calcium supplement on thoracic spinal nerve root pain caused by osteoporotic vertebral compression fracture.

METHODS: The 110 patients with osteoporotic vertebral compression fractures were randomly divided into two groups, with 55 cases in each group. Informed consent was obtained from patients of the two groups. This study was approved by the Hospital Ethics Committee. Pulsed radiofrequency group received pulsed radiofrequency treatment for vertebral compression fracture corresponding to dorsal root ganglion of spinal nerve. Nerve block group received nerve block treatment for corresponding dorsal root ganglion of spinal nerve. Both groups were treated with calcium carbonate D3, calcitonin and zoledronic acid for osteoporosis. Visual Analogue Scale and Oswestry Dysfunction Index results were compared between the two groups before and 1, 3, 6 and 12 months after treatment. The N-terminal propeptide of human procollagen type I and tartrate-resistant acid phosphatase isomer 5b levels were compared between the two groups.

RESULTS AND CONCLUSION: (1) The Visual Analogue Scale score and Oswestry Dysfunction Index were significantly improved in both groups after 1, 3, 6 and 12 months of treatment compared with those before treatment (P < 0.05). In 1 month after operation, there was no significant difference between the two groups (P > 0.05). In 3, 6 and 12 months after operation, the improvement of Visual Analogue Scale score and Oswestry Dysfunction Index in the pulsed radiofrequency group was better than that in the nerve block group (P < 0.05). (2) There was no significant difference in bone metabolism indexes N-terminal propeptide of human procollagen type I and tartrate-resistant acid phosphatase isomer 5b between the two groups at 1 month after operation and before operation (P > 0.05). N-terminal propeptide of human procollagen type I and tartrate-resistant acid phosphatase isomer 5b in the two groups were significantly improved at 3, 6 and 12 months after operation (P < 0.05). (3) Pulse radio frequency combined with guideline calcium supplement in the treatment of chest and back pain caused by osteoporotic vertebral compression fractures can not only noticeably reduce pain and improve the quality of life, but also fundamentally improve osteoporosis, with satisfactory short-term and long-term results.

Key words: pulse radiofrequency, osteoporosis, osteoporotic vertebral compression fracture, local nerve block, radicular pain

CLC Number:

R459.9|R683.2|R318

Nie Huiyong, Zhang Dandan, Bu Gang, Wang Suoliang, Lü Jun. Pulse radiofrequency combined with regular calcium supplement in the treatment of thoracic and back pain caused by osteoporotic vertebral compression fractures[J]. Chinese Journal of Tissue Engineering Research, 2019, 23(28): 4491-4496.

Figures/Tables 4

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