Predictive factors of refractures located in adjacent vertebrae after bone cement augmentation

doi:10.3969/j.issn.2095-4344.0350

Abstract

Abstract:

BACKGROUND: Percutaneous kyphoplasty (PKP) and percutaneous vertebroplasty (PVP) are effective treatments for osteoporotic vertebral compression fractures (OVCF), but studies have suggested that augmented vertebrae may lead to refracture located in adjacent vertebrae.

OBJECTIVE: To identify the characteristics and predictive factors of the adjacent and non-adjacent refractures after PKP and PVP.

METHODS: A retrospective analysis of 187 single-segment OVCF patients undergoing PKP or PVP was conducted. Clinical, imaging and surgical data were recorded and analyzed by chi-square, t test and Mann Whitney U test. The variants with P value < 0.2 were used for multiple logistic regression analysis.

RESULTS AND CONCLUSION: (1) Among 187 cases, 41 patients suffered refractures, and the total refracture rate was 21.9%. Twenty-three patients (56.1%) had refractures in the adjacent vertebrae, and 18 patients (43.9%) had refractures in the non-adjacent vertebrae. (2) The first fracture in thoracolumbar segment was the independent predictive factor for adjacent refratures in augmented vertebrae (P=0.017). Others (age, sex, height, body mass, presence or absence of diabetes mellitus, anti-osteoporosis treatment, history of fractures, cement leakage into interbody, cement diffusion, the bone cement volume injected, performed PKP or PVP, the percentage of anterior vertebral height restoration, the correction of the Cobb angle, bone mineral density, above or below of the refractured vertebrae compared to the augmented one) are not associated with the adjacent or non-adjacent refractures.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Fractures, Compression, Osteoporotic Fractures, Vertebroplasty, Tissue Engineering

CLC Number:

R318

Huang Tian-ji, Zhang Shi-yang, Lu Chao . Predictive factors of refractures located in adjacent vertebrae after bone cement augmentation[J]. Chinese Journal of Tissue Engineering Research, 2018, 22(27): 4342-4347.

Figures/Tables 3

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