中国组织工程研究 ›› 2025, Vol. 29 ›› Issue (27): 5933-5940.doi: 10.12307/2025.839

• 植入物相关大数据分析 Implant related big data analysis • 上一篇    

三维有限元法在股骨头坏死中应用的可视化分析

刘雨航,李宏宇,王  勇,王丰幸   

  1. 广西骨伤医院,广西壮族自治区南宁市   530000
  • 收稿日期:2024-06-26 接受日期:2024-08-28 出版日期:2025-09-28 发布日期:2025-03-07
  • 通讯作者: 李宏宇,博士,主任医师,广西骨伤医院,广西壮族自治区南宁市 530000
  • 作者简介:刘雨航,男,1999年生,江西省南昌市人,汉族,广西中医药大学2022级在读硕士,主要从事脊柱与四肢退行性疾病的中医防治研究。
  • 基金资助:
    南宁市青秀区科技计划项目(2020042),项目负责人:李宏宇;广西自然科学基金面上项目(2023GXNSFAA026208),项目负责人:李宏宇;广西自然科学基金面上项目(2014GXNSFAA118186),项目负责人:李宏宇

Visual analysis of application of three-dimensional finite element method in femoral head necrosis

Liu Yuhang, Li Hongyu, Wang Yong, Wang Fengxing   

  1. Guangxi Orthopedic Hospital, Nanning 530000, Guangxi Zhuang Autonomous Region, China

  • Received:2024-06-26 Accepted:2024-08-28 Online:2025-09-28 Published:2025-03-07
  • Contact: Li Hongyu, MD, Chief physician, Guangxi Orthopedic Hospital, Nanning 530000, Guangxi Zhuang Autonomous Region, China
  • About author:Liu Yuhang, Master candidate, Guangxi Orthopedic Hospital, Nanning 530000, Guangxi Zhuang Autonomous Region, China
  • Supported by:
    Nanning Qingxiu District Science and Technology Plan Project, No. 2020042 (to LHY); Guangxi Natural Science Fund Project (General Project), No. 2023GXNSFAA026208 (to LHY); Guangxi Natural Science Fund Project (General Project), No. 2014GXNSFAA118186 (to LHY)

摘要:

文题释义

股骨头坏死:是一种多见于由酒精、激素、创伤等因素诱发导致局部血供受到破坏,引起成骨细胞与破骨细胞平衡失调,继而发生股骨头结构改变甚至塌陷的难治性疾病,主要包括局部血运障碍、脂质代谢紊乱、骨细胞凋亡、免疫因素等多种机制作用。
有限元法:是一种在某个瞬时状态下通过构建虚拟模型、调整各项数据以模拟真实生物力学结构的手段,可用于评估和预测各类结构的应力分布及位移情况。

摘要
背景:有限元分析是一种广泛应用于工程技术领域的分析手段,但因其对复杂结构同样能做到高精度分析,在骨科领域的应用研究也逐年递增。近10年来,国内外利用有限元分析对股骨头坏死研究取得的成果数不胜数,但是尚缺乏对于当前研究现状和热点趋势的分析。
目的:对近年来有限元法应用于股骨头坏死领域的研究现状及热点进行可视化分析。
方法:从中国知网(CNKI)及Web of Science数据库中筛选出2014-2023年发表与股骨头坏死有限元分析相关的文章,利用Citespace 6.1.R6可视化分析软件对相关文献的主要研究内容进行归纳,并绘制出年度发文量、作者图谱、共被引文献、热点关键词等科学知识图谱,进行总结概括。
结果与结论:①根据相关关键词检索文献后导入Citespace软件,使用软件去重功能去除重复文章后,Web of Science核心合集相关文献385篇,CNKI数据库相关文献149篇;②其中关键词共现分析发现Web of Science数据库近10年间关键词频次排名为:finite element analysis(163次)、femoral head(83次)、arthroplasty(44次)、fixation(40次)、replacement(39次),中心性排名为:finite element method(0.21)、hip joint(0.21)、stability(0.19)、fixation(0.15)、contact pressure(0.15);③CNKI数据库近10年间关键词频次排名为:有限元分析(91次)、生物力学(45次)、股骨头坏死(42次)、股骨颈骨折(33次)、内固定(16次),中心性排名为:内固定(0.45)、3d打印(0.44)、健脾活骨方(0.43)、三维重建(0.42)、股骨头坏死(0.38);④近10年在股骨头坏死领域的研究中,国内外的发展均从“静态”发展为“动态”,整体进程基本上相似,对于步态模型及风险预测研究都较为深入;此外随着国内学者对于中药研究的深入,中医药手段治疗股骨头坏死疗效也得到了很好的验证;而在近10年内医学材料及计算机技术等领域将会成为国内外研究的热点;⑤尽管国内相关领域的研究较为迟缓,仍需更多临床研究验证,但随着国内科技技术的进步,相信国内学者会在未来将股骨头坏死有限元分析真正应用到临床,起到辅助患者个体化治疗、提升远期疗效的作用。

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱;骨折;内固定;数字化骨科;组织工程

关键词: 股骨头坏死, 有限元分析, 内固定, 步态模拟, 塌陷风险, 预测, 研究现状, 生物力学

Abstract: BACKGROUND: Finite element analysis is a kind of analysis method widely used in the field of engineering technology, but because of its characteristics of high precision analysis of complex structures, the application of finite element analysis in the field of orthopedics is also increasing year by year. In recent ten years, numerous achievements have been made in the study of femoral head necrosis by finite element analysis at home and abroad. However, the analysis of current research status and hot trends is still lacking.
OBJECTIVE: To visually analyze research status and hotspot of finite element method in the field of femoral head necrosis in recent years. 
METHODS: Articles related to finite element analysis of femoral head necrosis during 2014-2023 were selected from CNKI database and Web of Science database. Citespace 6.1.R6 visual analysis software was used to summarize the main research contents of relevant articles and draw the scientific knowledge graph such as the annual number of publications, author graph, co-citation papers and hot keywords for summary. 
RESULTS AND CONCLUSION: (1) After literature retrieval according to relevant keywords, Citespace software was imported. After software deduplication function was used to remove duplicate articles, Web of Science core collected 385 related articles and CNKI database 149 related articles. (2) The keyword co-occurrence analysis found that the keyword frequency ranking in Web of Science database in recent ten years was as follows: finite element analysis (163 times), femoral head (83 times), arthroplasty (44 times), fixation (40 times), and replacement (39 times); centrality ranking: finite element method (0.21), hip joint (0.21), stability (0.19), fixation (0.15), and contact pressure (0.15). (3) The ranking of keywords frequency in CNKI database in recent ten years was as follows: finite element analysis (91 times), biomechanics (45 times), femoral head necrosis (42 times), femoral neck fracture (33 times), internal fixation (16 times), and the centrality ranking was as follows: internal fixation (0.45), 3D printing (0.44), Jianpi Huogu formula (0.43), three-dimensional reconstruction (0.42), and femur head necrosis (0.38). (4) In the past ten years, the research in the field of femoral head necrosis had developed from “static” to “dynamic”' at home and abroad. The overall process was basically similar, and the research on gait model and risk prediction was more in-depth. In addition, with the deepening of domestic scholars’ research on traditional Chinese medicine, the curative effect of traditional Chinese medicine in the treatment of femoral head necrosis had also been well verified. In the past ten years, the fields of medical materials and computer technology can become the focus of research at home and abroad. (5) Although the research in related fields in China is relatively slow, more clinical studies are still needed to verify. However, with the progress of science and technology in China, it is believed that domestic scholars will truly apply the finite element analysis of femoral head necrosis to clinical practice in the future, and play a role in assisting patients with individualized treatment and improving long-term efficacy.

Key words: femoral head necrosis, finite element analysis, internal fixation, gait simulation, collapse risk, prediction, research status, biomechanics

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