中国组织工程研究 ›› 2025, Vol. 29 ›› Issue (9): 1876-1882.doi: 10.12307/2025.128

• 骨与关节图像与影像Bone and joint imaging • 上一篇    下一篇

影像三维重建安全辅助单孔分体内镜治疗L5/S1极外侧腰椎间盘突出症

冯志萌,孙  宁,孙兆忠,李岳飞,刘昌震,李  洒   

  1. 滨州医学院附属医院脊柱外科,山东省滨州市   256603
  • 收稿日期:2023-11-30 接受日期:2024-01-22 出版日期:2025-03-28 发布日期:2024-10-10
  • 通讯作者: 孙兆忠,主任医师,滨州医学院附属医院脊柱外科,山东省滨州市 256603
  • 作者简介:第一作者:冯志萌,男,1997年生,山东省滨州市人,汉族,滨州医学院在读硕士,主要从事微创脊柱外科方面的研究。
  • 基金资助:
    国家重点研发计划资助项目(2017YFC0114002),子项目负责人:孙兆忠;山东省自然科学基金资助项目(ZR2017LH021),项目负责人:孙兆忠;滨州市社会发展科技创新计划(2023SHFZ034),项目负责人:孙兆忠

Three-dimensional image reconstruction can safely assist one-hole split endoscope in treatment of #br# L5/S1 far lateral lumbar disc herniation

Feng Zhimeng, Sun Ning, Sun Zhaozhong, Li Yuefei, Liu Changzhen, Li Sa   

  1. Department of Spinal Surgery, Binzhou Medical University Hospital, Binzhou 256603, Shandong Province, China

  • Received:2023-11-30 Accepted:2024-01-22 Online:2025-03-28 Published:2024-10-10
  • Contact: Sun Zhaozhong, Chief physician, Department of Spinal Surgery, Binzhou Medical University Hospital, Binzhou 256603, Shandong Province, China
  • About author:Feng Zhimeng, Master candidate, Department of Spinal Surgery, Binzhou Medical University Hospital, Binzhou 256603, Shandong Province, China
  • Supported by:
    National Key Research and Development Program, No. 2017YFC0114002 (to SZZ); Shandong Natural Science Foundation of China, No. ZR2017LH021 (to SZZ); Binzhou Social Development Science and Technology Innovation Program, No. 2023SHFZ034 (to SZZ)

摘要:

文题释义:

极外侧腰椎间盘突出症:指突出物位于椎间孔内或外的腰椎间盘突出,其直接压迫椎间孔内的出口神经根或背根神经节,主要临床表现为剧烈的神经根性疼痛。
影像三维重建:将患者腰椎CT数据资料导入Mimics 21.0软件中,重建出腰椎三维模型,在模型上观测与内镜下结构相一致的解剖学
指标。

摘要
背景:单孔分体内镜作为一种新型的内镜技术,适用于治疗极外侧腰椎间盘突出症。但目前国内外针对L5/S1这一发病率极低的极外侧腰椎间盘突出症的研究资料甚少,尚无详尽描述单孔分体内镜治疗L5/S1极外侧腰椎间盘突出症的影像解剖学资料。
目的:通过影像三维重建确定骨性标志点,并以该标志点准确定位L5出口神经根、L5/S1椎间隙及其他结构之间的位置关系,辅助单孔分体内镜经后外侧入路实现对L5出口神经根的减压,治疗L5/S1极外侧腰椎间盘突出症。
方法:选择符合纳入标准的29例L5/S1单侧极外侧腰椎间盘突出症患者,其中男12例,女17例;年龄48-74岁。将患者的腰椎CT数据资料导入Mimics 21.0软件中重建腰椎三维模型。测量L5/S1相关参数:①在横突根部下缘与峡部外侧缘的交点(H)所在矢状面上测量:H分别至L5出口神经根上缘、下缘的垂直距离(a1,a2);H分别至L5下终板、S1上终板的垂直距离(b1,b2);H至L5椎弓根下缘的垂直距离(c);②H至L5椎弓根内侧壁所在矢状面的左右水平距离(d);③H至硬脊膜外侧缘所在矢状面的左右水平距离(e);④H至L5下终板最外侧缘所在矢状面的左右水平距离(f);⑤在L5下终板最外侧缘所在矢状面上测量:H所在横断面分别至L5出口神经根上缘、下缘的垂直距离(g1,g2);H所在横断面分别至L5下终板、S1上终板的垂直距离(h1,h2);⑥H至L5出口神经根最后缘所在冠状面的前后水平距离(i);⑦骶骨翼后缘最高点至L5下终板最后缘所在冠状面的前后水平距离(j)。

结果与结论:①男女之间各相关测量参数相比差异无显著性意义(P > 0.05);②a1,a2,b1,b2,c,d,e,f,h1,h2,g1,g2,i,j患侧与健侧相比差异无显著性意义(P > 0.05);③观测发现,a1与c之间相比差异无显著性意义(P > 0.05),表明椎弓根下缘即为L5出口神经根上缘,L5出口神经根紧贴椎弓根下缘并经L5椎体后方向前外侧走行,H均位于L5出口神经根上方;④以H作为骨性标志点,无需向上探查,无需磨除峡部,只需向下、向外侧磨除部分骨质显露L5出口神经根与椎间隙,向内侧有足够的安全距离避免损伤硬脊膜来完成侧隐窝、椎间孔区域的探查减压;⑤术者可在H、L5下终板最外侧缘所在的矢状面及L5横突与骶骨翼构成的“矩形区域”内进行操作,越靠近内下方区域(Kambin三角)越安全;⑥提示单孔分体内镜经后外侧入路治疗L5/S1 极外侧腰椎间盘突出症,在镜下以H作为骨性标志点定位L5出口神经根及椎间隙,能实现对L5出口神经根的精准、安全、有效减压。


中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱;骨折;内固定;数字化骨科;组织工程

关键词: 极外侧腰椎间盘突出症, 单孔分体内镜, 影像三维重建, 骨性标志, 数字化软件

Abstract: BACKGROUND: One-hole split endoscope as a new type of endoscopic technique is suitable for the treatment of far lateral lumbar disc disease. However, there are few research data on L5/S1, which has a very low incidence of far lateral lumbar disc herniation at home and abroad, and there is no detailed image anatomical data describing the one-hole split endoscope treatment of L5/S1 far lateral lumbar disc herniation.
OBJECTIVE: Through the three-dimensional image reconstruction, the bony landmarks were determined to accurately locate the positional relationship between the L5 outlet nerve root, the L5/S1 intervertebral space and other structures. One-hole split endoscope via posterolateral approach was used to accurately, safely and effectively decompress the L5 outlet nerve root and treat the L5/S1 far lateral lumbar disc herniation.
METHODS: Twenty-nine patients with L5/S1 unilateral far lateral lumbar disc herniation who met the inclusion and exclusion criteria were selected, including 12 males and 17 females at the age of 48-74 years. The lumbar CT data of the patients were imported into Mimics 21.0 software to reconstruct the three-dimensional lumbar model. Measurement of L5/S1 related parameters: (1) Measurement on the sagittal plane at the intersection (H) of the lower edge of the transverse process and the lateral edge of the isthmus: The vertical distance between H and the upper and lower edges of L5 outlet nerve root (a1, a2); the vertical distance between H and the lower endplate of L5 and the upper endplate of S1 (b1, b2); vertical distance from the lower edge of the pedicle from H to L5 (c). (2) Horizontal distance between the left and right sides of the sagittal surface where the medial wall of the pedicle was located from H to L5 (d). (3) The horizontal distance from H to the left and right side of the sagittal plane where the lateral margin of the dura was located (e). (4) Horizontal distance (f) between the left and right sides of the sagittal plane at the outermost edge of the lower endplate from H to L5. (5) Measurements were made on the sagittal plane where the outermost edge of the lower endplate of L5: The vertical distance between the cross section of H and the upper and lower edges of L5 outlet nerve root (g1, g2); vertical distance (h1, h2) between the transverse section of H and the lower endplate of L5 and the upper endplate of S1, respectively; (6) anteroposterior horizontal distance from H to L5 in the coronal plane where the last edge of the nerve root exits (i); (7) anteroposterior horizontal distance from the highest point of the posterior margin of the sacral wing to the last margin of the inferior endplate of L5 in the coronal plane (j).
RESULTS AND CONCLUSION: (1) There was no significant difference in the relevant measurement parameters between men and women (P > 0.05). (2) a1, a2, b1, b2, c, d, e, f, h1, h2, g1, g2, i, and j on the affected side were not significantly different from the healthy side (P > 0.05). (3) There was no significant difference between a1 and c (P > 0.05), indicating that the lower edge of the pedicle was the upper edge of the L5 outlet nerve root; the L5 outlet nerve root was close to the lower edge of the pedicle and ran anterolateral behind the L5 vertebral body, and H was located above the L5 outlet nerve root. (4) With H as the bony marker point, it was not necessary to probe upward or to remove the isthmus, but only to grind part of the bone downward and laterally to reveal the L5 outlet nerve root and vertebral space, and to have enough safe distance to avoid damage to the dural membrane to complete exploration and decompression of the lateral recess and foraminal region. (5) The surgeon could operate in the sagittal plane where the most lateral edge of the L5 inferior endplate was located, and in the “rectangular area” formed by the L5 transverse process and the sacral wing. The closer to the medial and inferior area (Kambin triangle), the safer the operation was. (6) It is suggested that using H as the bony landmark point to locate the L5 outlet nerve root and intervertebral space through one-hole split endoscope via posterolateral approach can achieve accurate, safe and effective decompression of L5/S1 far lateral lumbar disc herniation.

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱;骨折;内固定;数字化骨科;组织工程

Key words:  far lateral lumbar disc herniation, one-hole split endoscope, three-dimensional image reconstruction, bony landmark, digital software

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