中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (30): 5665-5668.doi: 10.3969/j.issn.1673-8225.2011.30.038

• 骨与关节学术探讨 academic discussion of the bone and joint • 上一篇    下一篇

脊柱结核外科治疗骨缺损的修复

杨智贤，彭小忠，武振国，韦涵渝，雷成刚，黄站珠   

  1. 柳州市工人医院脊柱外科，广西壮族自治区柳州市   545005
  • 收稿日期:2011-03-05 修回日期:2011-06-20 出版日期:2011-07-23 发布日期:2011-07-23
  • 通讯作者: 彭小忠，副主任医师，柳州市工人医院/广西医科大学第四附属医院脊柱外科，广西壮族自治区柳州市545005 pxz@163.com
  • 作者简介:杨智贤，男，1965年，陕西省西安市人，汉族，1989年苏州大学毕业，副主任医师，主要从事脊柱创作及骨病研究。 yangzhixiann@163.com

Bone defect repair in the surgical treatment of spinal tuberculosis

Yang Zhi-xian, Peng Xiao-zhong, Wu Zhen-guo, Wei Han-yu, Lei Cheng-gang, Huang Zhan-zhu   

  1. Department of Spinal Surgery, Liuzhou Worker’s Hospital, Liuzhou  545005, Guangxi Zhuang Autonomous Region, China
  • Received:2011-03-05 Revised:2011-06-20 Online:2011-07-23 Published:2011-07-23
  • Contact: Peng Xiao-zhong, Associate chief physician, Department of Spinal Surgery, Liuzhou Worker’s Hospital, Liuzhou 545005, Guangxi Zhuang Autonomous Region, China pxz@163.com
  • About author:Yang Zhi-xian, Associate chief physician, Department of Spinal Surgery, Liuzhou Worker’s Hospital, Liuzhou 545005, Guangxi Zhuang Autonomous Region, China yangzhixiann@163.com

PDF

435

被引次数

16

摘要：

背景：脊柱结核外科干预治疗中如何有效修复破坏之椎体，是脊柱结核治疗中的重点和难点。
目的：探讨国内目前脊柱结核病灶清除后骨缺损修复方法、骨缺损修复的有效方法及新进展。
方法：CNKI数据库检索2006/2010-01-01五年间相关脊柱结核外科治疗文献，先检索关键词“脊柱结核”，再分别以：“内固定”，“植骨”，“人工骨(材料)”，“钛网”， “骨水泥”，“人工椎体”，为关键词在以上数据中检索，根据入选条件，选择相关文献，对其文献报道病例、手术方法(包括骨修复方法)、疗效(包括治愈率、复发率、Cobb角纠正)进行统计分析。
结果与结论：自体骨(髂骨、肋骨)是脊柱结核目前骨缺损的主要修复来源，其次是钛网植骨，人工骨及人工椎体少量用于临床治疗。提示，自体骨仍是脊柱结核骨缺损修复的主要来源，是钛网植骨次之，人工骨及人工椎体有广阔的发展空间，成为将来植骨理想替代品。

关键词: 人工骨(材料), 脊柱结核, 病灶清除术, 植骨, 内固定

Abstract:

BACKGROUND: How to repair damage to the vertebral body using surgical methods is important and difficult for treatment of spinal tuberculosis
OBJECTIVE: To learn a variety of the methods to repair bone defects in spinal tuberculosis after lesions removal in China at present, and to find out the effective methods and new progress.
METHODS: CNKI database was search for  the literature related to surgical treatment of spinal tuberculosis published 2006/2010-01-01. First, the key word of “spinal tuberculosis” was used and then “internal fixation”, “bone graft”, “synthetic bone (materials)”, “titanium mesh”, “bone cement”, “artificial vertebral body” were used as key words in the above data retrieval. According to selected conditions, the relevant literature with reported cases, surgical procedures (including bone repair method), effects (including cure rate, relapse rate, Cobb angle corrected) were selected for statistical analysis.
RESULTS AND CONCLUSION: Autologous bone (iliac, ribs) is the major source of repaired bone defects in spinal tuberculosis, followed by titanium mesh and bone graft, and a small amount of synthetic bone and artificial vertebral body is used for clinical treatment. In the future, synthetic bone and the artificial vertebral body have a broad development space, being an ideal substitute.

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