中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (22): 4082-4085.doi: 10.3969/j.issn.1673-8225.2010.22.023

• 骨与关节学术探讨 academic discussion of the bone and joint • 上一篇    下一篇

人工髋关节假体材料磨损性能及其影响因素

张建林，赵俊华，叶  军，栾彦军   

  1. 延安大学附属医院骨一科，陕西省延安市  716000
  • 出版日期:2010-05-28 发布日期:2010-05-28
  • 作者简介:张建林，男，1974年生，主要从事关节，关节镜，椎间盘镜方面的研究。Zjl1939@163.com

Wearing performance of hip prosthesis materials and the influential factors

Zhang Jian-lin, Zhao Jun-hua, Ye Jun, Luan Yan-jun   

  1. First Department of Orthopedics, Affiliated Hospital of Yanan University, Yanan  716000, Shaanxi Province, China
  • Online:2010-05-28 Published:2010-05-28
  • About author:Zhang Jian-lin, First Department of Orthopedics, Affiliated Hospital of Yanan University, Yanan 716000, Shaanxi Province, China Zjl1939@163.com

PDF

1245

被引次数

16

摘要：

目的：比较不同人工髋关节材料的磨损性能，提出预防假体松动的措施。
方法：以 “假体松动，人工髋关节，磨损，磨损颗粒，髋关节假体为中文关键词；以:“prosthesis loosening，hip，wear debris，hip prosthesis” 为英文关键词，采用计算机检索1993-01/2009-10相关文章。纳入与人工髋关节假体的磨损及其影响因素相关的文章；排除重复研究或Meta分析类文章。以28篇文献为主重点进行分析人工髋关节假体材料摩擦磨损性能及其影响因素。
结果：髋关节手术的方法、假体安装的技术及关节负重引起的假体与宿主骨之间的微动等机械性因素可能是人工髋关节假体松动的启动因素，而生物学因素-磨损颗粒可能调节着人工髋关节假体松动的后期过程，因此对机械性和生物学因素的研究可能会揭示人工髋关节假体松动的奥秘。
结论：人工关节磨损产生微小磨损颗粒是人工关节后期松动的关键因素。通过对宿主骨质量的提高及对假体设计和材料的研究进一步深入，可以更好地预防和治疗髋关节假体的松动。

关键词: 人工髋关节, 假体松动, 磨损, 磨损颗粒, 影响因素

Abstract:

OBJECTIVE: To compare the wearing performance of different artificial hip joint materials to propose measures for preventing prosthesis loosening.
METHODS: A computer-based online search was performed for related articles published between January 1993 and October 2009 with key words “prosthesis loosening, hip, wear debris, hip prosthesis” in Chinese and English. Articles related to artificial hip prosthesis wearing and the influential factors were included. Repetitive studies or Meta analysis were excluded. A total of 28 articles regarding artificial hip prosthesis wearing and the influential factors were included.
RESULTS: Operation methods, prosthesis installation, joint weight loading-induced micromovement between prosthesis and host bone are contributed to hip prosthesis loosening. The biological factor-wear debris may regulate late process of hip prosthesis loosening. Therefore, studies of mechanical and the biological factors may reveal cause of hip prosthesis loosening.
CONCLUSION: Joint prosthesis wearing-induced wear debris is a key factor in the late process of hip prosthesis loosening. Improvement of host bone quality and prosthesis design and materials can better prevent and treat hip prosthesis loosening.

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