中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (21): 3891-3894.doi: 10.3969/j.issn.1673-8225.2010.21.021

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

非黏附性液体栓塞材料ONYX与脑动静脉畸形的治疗

朱远群   

  1. 广西医科大学第四附属医院神经内科,广西壮族自治区柳州市  545005
  • 出版日期:2010-05-21 发布日期:2010-05-21
  • 作者简介:朱远群★,女,1973年生,广西壮族自治区贺州市邵平县人,汉族,2006年广西医科大学毕业,硕士,主治医师,主要从事脑血管病的临床与康复研究工作。 zhyqgxlz0618@sina.com

Non-adhesive liquid embolic material ONYX treatment of cerebral arteriovenous malformations

Zhu Yuan-qun   

  1. Department of Neurology, Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou   545005, Guangxi Zhuang Autonomous Region, China
  • Online:2010-05-21 Published:2010-05-21
  • About author:Zhu Yuan-qun★, Master, Attending physician, Department of Neurology, Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou 545005, Guangxi Zhuang Autonomous Region, China zhyqgxlz0618@sina.com

摘要:

目的:探讨非黏附性液体栓塞材料ONYX的优势与不足及其在脑动静脉畸形中的应用效果和栓塞技巧。
方法:应用中国知网(CNKI)、万方医学网数据库,由第一作者以“脑动静脉畸形;栓塞;非黏附性液体栓塞材料;ONYX;氰基丙烯酸正丁酯;栓塞技巧”检索1998/2010时限内,与非黏附性液体栓塞材料ONYX优势和不足、在脑动静脉畸形中的临床应用效果及其栓塞技巧相关文献。排除重复研究或较陈旧文献。
结果:依据纳入排除标准共保留相关文献20篇。非黏附性液体栓塞材料ONYX不黏管,在畸形血管团内弥散好,可以缓慢注射,栓塞率高,栓塞效果永久,无再通现象,栓塞后易于手术切除,是治疗脑动静脉畸形较为理想的栓塞材料。但有一定并发症,需注意掌握栓塞技巧。
结论:ONYX是治疗脑动静脉畸形较为理想的栓塞材料,需要掌握栓塞的技巧,减少并发症的发生。

关键词: 脑动静脉畸形, 栓塞, 非黏附性液体栓塞材料, ONYX, 氰基丙烯酸正丁酯, 栓塞技巧

Abstract:

OBJECTIVE: To investigate the advantages and disadvantages, as well as the application effects and embolization techniques of non-adhesive liquid embolic material ONYX in cerebral arteriovenous malformation.
METHODS: CNKI database and Wanfang database were retrieved from 1998 to 2010 by the first author using “cerebral arteriovenous malformation, embolism, non-adhesive liquid embolic material, ONYX, butyl cyanoacrylate, embolization techniques” in Chinese as key words, for articles related to advantages and disadvantages of non-adhesive liquid embolic material ONYX, as well as clinical effect and embolization techniques on cerebral arteriovenous malformation. Reproducible study or obsolete literature were excluded.
RESULTS: According to the inclusion and exclusion criteria, 20 literatures were involved in the analysis. Non-adhesive liquid embolic material ONYX do not stick in tube and well disperse in the malformed blood vessel group, it can be slowly injected, exhibit a high embolization rate, permanent embolization effect and non-reperfusion phenomenon, also it is easy for surgical resection after embolization, so non-adhesive liquid embolic material ONYX is an ideal embolization material for the treatment of cerebral arteriovenous malformations. However, certain complications may occur, and techniques should be mastered to treat embolization.
CONCLUSION: ONYX is a kind of ideal embolic materials for the treatment of cerebral arteriovenous malformations, physicians should master the embolization skills to reduce complications.

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