中国组织工程研究

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前屈后伸载荷下颈椎间孔的孔径变化:Bryan颈人工椎间盘置换与颈椎钢板植骨内固定的比较

陈书文1,尹朝信1,颜爱民1,刘文和2   

  1. 1桂阳中医院骨科,湖南省桂阳市  424400;2湘南学院附属医院骨科,湖南省郴州市 423000
  • 出版日期:2010-07-23 发布日期:2010-07-23
  • 通讯作者: 刘文和,博士,副主任医师,湘南学院附属医院骨科,湖南省郴州市 423000
  • 作者简介:陈书文,男,1967年生,湖南省桂阳县人,汉族,1990年湖南中医药大学毕业,副主任医师,主要从事老年病、骨质疏松症的研究。 liudoct@163.com

Adaptive variation of the space of intervertebral foramina under anteflexion and posterior extension conditions: Bryan cervical disc prosthesis replacement versus cervical plate combined with graft internal fixation

Chen Shu-wen1, Yin Chao-xin1, Yan Ai-min1, Liu Wen-he2   

  1. 1 Department of Orthopaedics, Guiyang Hospital of Traditional Chinese Medicine, Guiyang  424400, Hunan  Province, China; 2 Department of Orthopaedics, Affiliated Hospital of Xiangnan Univerisity, Chenzhou  423000, Hunan Province, China
  • Online:2010-07-23 Published:2010-07-23
  • Contact: Liu Wen-he, Department of Orthopaedics, Affiliated Hospital of Xiangnan University, Chenzhou 423000, Hunan Province, China
  • About author:Chen Shu-wen, Associate chief physician, Department of Orthopaedics, Guiyang Hospital of Traditional Chinese Medicine, Guiyang 424400, Hunan Province, China liudoct@163.com

摘要:

背景:诸多针对脊椎椎体间固定融合后相邻节段应力变化的生物力学测试结果并不尽相同,载荷控制与位移控制试验模式下所反映出的相邻节段应力状况其结果也相差甚远。
目的:分析椎间盘完整、椎间盘切除、Bryan颈人工椎间盘置换和前路颈椎植骨融合钢板内固定后,成人尸体颈椎标本分别在前屈后伸载荷下C5/6椎间孔孔径和面积的变化情况。
方法:分别测量C 5/6椎间盘完整、椎间盘髓核摘除、Bryan颈人工椎间盘置换和前路钢板植骨内固定4种状态下以0.25,0.50,0.75,1.00,1.25,1.50 N•m的分级载荷加载于标本的前屈后伸状态时C 5/6椎间孔孔径和面积的变化情况。
结果与结论:前屈后伸各级加载时,C 5/6椎间孔上下径、上前后径、下前后径和面积椎间盘完整组、Bryan颈人工置换组和钢板植骨内固定组高于椎间盘髓核摘除组,差异有显著性意义(P < 0.05),Bryan颈人工置换组高于钢板植骨内固定组,差异有显著性意义(P < 0.05),可见颈椎间盘髓核摘除后C 5/6椎间孔有效空间明显减少。

关键词: 颈椎, 椎间孔, 椎间盘摘除, 钢板, 生物力学

Abstract:

BACKGROUND: Many reports have shown different experiment results about the biomechanical test effects of the stress on the adjacent segments of vertebra with interbody fusion. The experiment results are very different of the stress characteristic on the adjacent segments of vertebra with interbody fusion under the conditions of loading control and shifting control test mode.
OBJECTIVE: To analyze adaptive variation of the space of intervertebral foramina C5/6 basing on graded-loading-force under forward flexion and rearward extended conditions under different conditions of intact cervical disc, cervical intervertebral discectomy, Bryan cervical disc prosthesis replacement, or anterior cervical discectomy and fusion using bone graft and plate fixation.
METHODS: The pathologic variational regulation of the space of bone intervertebral foramina C5/6 had been analyzed under different graded-loading-force (0.25, 0.50, 0.75, 1.00, 1.25 and 1.50 N•m) in forward flexion and rearward extended under different conditions of intact cervical disc, cervical intervertebral discectomy, Bryan cervical disc prosthesis replacement, or anterior cervical discectomy and fusion using bone graft and plate fixation.
RESULTS AND CONCLUSION: Under the different conditions of graded-loading-force in forward flexion and rearward extended conditions, on adult’s corpse cervical spine samples, the length diameter, superior width, inferior width and space of bone intervertebral foramina of C5/6 of the cervical intervertebral discectomy group was lower than that of the other groups (P < 0.05), the Bryan cervical disc prosthesis replacement group was higher than cervical intervertebral discectomy group (P < 0.05). The experiment results have shown that the average area data of space of bone intervertebral foramina C5/6 decreases after cervical intervertebral discectomy.

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