Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (2): 289-293.doi: 10.3969/j.issn.2095-4344.2015.02.024

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Moxibustion: its outlook in the intestinal flora and mucosal immunity for regulation of irritable bowel syndrome

Zhao Ji-meng1, Huang Yan1, Dou Chuan-zi1, Wang Shuo-shuo2, Wang Xiao-mei1, Li Yin-he1, Bao Chun-hui1, Zhou Ci-li1, Weng Zhi-jun1, Lu Yuan1, Wu Huan-gan1   

  1. 1Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; 2Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China
  • Received:2014-12-17 Online:2015-01-08 Published:2015-01-08
  • Contact: author: Wu Huan-gan, Professor, Doctoral supervisor, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China Corresponding author: Lu Yuan, Physician, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
  • About author:Zhao Ji-meng, Studying for doctorate, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
  • Supported by:
     the National Basic Research Program of China (973 Program), No. 2015CB554500; the National Natural Science Foundation of China for the Youth, No. 81403474; the Natural Science Foundation of Shanghai, No. 14ZR1438700
     

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Abstract:

BACKGROUND: The interaction and mutual influence of intestinal flora in the host intestine with mucosal immune barrier play an important role in the homeostasis regulation within the intestine.
OBJECTIVE: To explore the role of intestinal flora in the pathogenesis of irritable bowel syndrome and the mechanism of moxibustion in the treatment of irritable bowel syndrome from the aspects of intestinal flora imbalance and mucosal immune activation. 
METHODS: With the key words of “irritable bowel syndrome, intestinal flora, intestinal immune, moxibustion” in Chinese and in English, respectively, a computer-based search was performed for articles published in CNKI, VIP and PubMed databases from October 2001 to October 2014. After the initial screening, the reserved articles were further detailed, summarized and concluded.
RESULTS AND CONCLUSION: Totally 37 articles were collected, including 15 in Chinese and 22 in English. The analysis results showed that, the imbalance of intestinal flora and mucosal immune can play an important role in the pathogenesis of irritable bowel syndrome, and the former one can affect the body’s feeling of rectal distension threshold and visceral sensitivity. Moxibustion excels at improvement of the symptoms of irritable bowel syndrome, particularly abdominal pain with high visceral sensitivity, by regulating the body’s physiological balance from multi-link and multi-target aspects.



中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程


全文链接：

Key words: Moxibustion, Irritable Bowel Syndrome, Immunity

CLC Number: